Curation Details
Interaction ID: MINT-6174980

Unique identifier for interactor Auniprotkb:P49768
Unique identifier for interactor Buniprotkb:Q92542
Alternative identifier for interactor Aintact:EBI-297277
uniprotkb:O95465
uniprotkb:Q14762
uniprotkb:Q15719
uniprotkb:Q15720
uniprotkb:Q96P33
uniprotkb:Q9UIF0
uniprotkb:B2R6D3
ensembl:ENSP00000326366.5
ensembl:ENSP00000451915.2
ensembl:ENSP00000514903.1
ensembl:ENSP00000514904.1
ensembl:ENSP00000514905.1
ensembl:ENSP00000514933.1
ensembl:ENSP00000514944.1
ensembl:ENSP00000514948.1
ensembl:ENSP00000514950.1
ensembl:ENSP00000514966.1
ensembl:ENSP00000514968.1
Alternative identifier for interactor Bintact:EBI-998440
uniprotkb:Q86VV5
uniprotkb:Q5T207
uniprotkb:Q5T208
ensembl:ENSP00000294785.5
Aliases for Apsi-mi:psn1_human(display_long)
uniprotkb:PSEN1(gene name)
psi-mi:PSEN1(display_short)
uniprotkb:AD3(gene name synonym)
uniprotkb:PS1(gene name synonym)
uniprotkb:PSNL1(gene name synonym)
uniprotkb:Protein S182(gene name synonym)
Aliases for Bpsi-mi:nica_human(display_long)
uniprotkb:NCSTN(gene name)
psi-mi:NCSTN(display_short)
uniprotkb:KIAA0253(gene name synonym)
uniprotkb:UNQ1874/PRO4317(orf name)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorMorais et al. (2008)
Identifier of the publicationpubmed:18201567
imex:IM-13963
mint:MINT-6174903
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7775262
mint:MINT-6174980
imex:IM-13963-6
Confidence scoreintact-miscore:0.79
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F3A
comment:The interaction, although to a minor extent, was also verified with mutants of hNTC localizing in late lysosomes, trans-Golgi, and plasma membrane
comment:homomint
comment:mint
dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293t)
taxid:9606(Homo sapiens HEK293T embryonic kidney cell)
Parameters of the interaction-
Creation date2008/02/07
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot