Curation Details
Interaction ID: MINT-6174932

Unique identifier for interactor Auniprotkb:P11279
Unique identifier for interactor Buniprotkb:Q92542
Alternative identifier for interactor Aintact:EBI-2805407
uniprotkb:Q9NP13
uniprotkb:Q8WU33
uniprotkb:Q9BRD2
uniprotkb:Q96I40
uniprotkb:B4DWL3
ensembl:ENSP00000333298.4
Alternative identifier for interactor Bintact:EBI-998440
uniprotkb:Q5T207
uniprotkb:Q5T208
ensembl:ENSP00000294785.5
uniprotkb:Q86VV5
Aliases for Apsi-mi:lamp1_human(display_long)
uniprotkb:CD107 antigen-like family member A(gene name synonym)
uniprotkb:LAMP1(gene name)
psi-mi:LAMP1(display_short)
Aliases for Bpsi-mi:nica_human(display_long)
uniprotkb:NCSTN(gene name)
psi-mi:NCSTN(display_short)
uniprotkb:KIAA0253(gene name synonym)
uniprotkb:UNQ1874/PRO4317(orf name)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorMorais et al. (2008)
Identifier of the publicationpubmed:18201567
imex:IM-13963
mint:MINT-6174903
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7775036
mint:MINT-6174932
imex:IM-13963-3
Confidence scoreintact-miscore:0.27
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F2A
comment:"\"To target hNCT to late endosomes/lysosomes (hNCTLL), the cytoplasmic domain was fused with a C-terminal dileucine motif present on BACE (DDxxLL), previously described to be required for its normal targeting to that intracellular location\""
comment:homomint
comment:mint
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hela)
taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)
Parameters of the interaction-
Creation date2008/02/07
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bha tag:?-?(MINT-6180295)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AImmunostaining
Participant identification method for interactor BImmunostaining