Curation Details
Interaction ID: MINT-60133

Unique identifier for interactor Auniprotkb:P06240
Unique identifier for interactor Buniprotkb:P22681
Alternative identifier for interactor Aintact:EBI-1401
ensembl:ENSMUSP00000066209.5
ensembl:ENSMUSP00000099656.2
uniprotkb:Q62320
uniprotkb:Q61795
uniprotkb:Q61794
uniprotkb:Q91X65
Alternative identifier for interactor Bintact:EBI-518228
uniprotkb:A3KMP8
ensembl:ENSP00000264033.3
Aliases for Apsi-mi:lck_mouse(display_long)
uniprotkb:Lck(gene name)
psi-mi:Lck(display_short)
uniprotkb:Lsk-t(gene name synonym)
uniprotkb:Lymphocyte cell-specific protein-tyrosine kinase(gene name synonym)
uniprotkb:p56-LCK(gene name synonym)
uniprotkb:Leukocyte C-terminal Src kinase(gene name synonym)
Aliases for Bpsi-mi:cbl_human(display_long)
uniprotkb:Signal transduction protein CBL(gene name synonym)
uniprotkb:Proto-oncogene c-Cbl(gene name synonym)
uniprotkb:Casitas B-lineage lymphoma proto-oncogene(gene name synonym)
uniprotkb:RING finger protein 55(gene name synonym)
uniprotkb:CBL(gene name)
psi-mi:CBL(display_short)
uniprotkb:CBL2(gene name synonym)
uniprotkb:RNF55(gene name synonym)
uniprotkb:RING-type E3 ubiquitin transferase CBL(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorHawash et al. (2002)
Identifier of the publicationpubmed:11741956
mint:MINT-5214911
NCBI Taxonomy identifier for interactor Ataxid:10090(mouse)
taxid:10090(Mus musculus)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8061788
mint:MINT-60133
Confidence scoreintact-miscore:0.52
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F6A
comment:W97A mutation in LCK does not totally abrogate binding
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
NCBI Taxonomy identifier for the host organismtaxid:9606(human-jurkat)
taxid:9606(Homo sapiens Jurkat T-cell leukemia cell)
Parameters of the interaction-
Creation date2005/07/08
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:63-118(MINT-596302)
mutation decreasing interaction:97-97(MINT-596305)
Feature(s) for interactor Btag:?-?(MINT-596296)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APolyclonal antibody western blot
Participant identification method for interactor BNucleotide sequence identification