| Unique identifier for interactor A | uniprotkb:P49768 |
| Unique identifier for interactor B | uniprotkb:O35430 |
| Alternative identifier for interactor A | intact:EBI-297277 uniprotkb:O95465 uniprotkb:Q14762 uniprotkb:Q15719 uniprotkb:Q15720 uniprotkb:Q96P33 uniprotkb:Q9UIF0 uniprotkb:B2R6D3 ensembl:ENSP00000326366.5 ensembl:ENSP00000451915.2 ensembl:ENSP00000514903.1 ensembl:ENSP00000514904.1 ensembl:ENSP00000514905.1 ensembl:ENSP00000514933.1 ensembl:ENSP00000514944.1 ensembl:ENSP00000514948.1 ensembl:ENSP00000514950.1 ensembl:ENSP00000514966.1 ensembl:ENSP00000514968.1 |
| Alternative identifier for interactor B | intact:EBI-704760 ensembl:ENSRNOP00055044768 ensembl:ENSRNOP00060030323 ensembl:ENSRNOP00065034956 |
| Aliases for A | psi-mi:psn1_human(display_long) uniprotkb:PSEN1(gene name) psi-mi:PSEN1(display_short) uniprotkb:AD3(gene name synonym) uniprotkb:PS1(gene name synonym) uniprotkb:PSNL1(gene name synonym) uniprotkb:Protein S182(gene name synonym) |
| Aliases for B | psi-mi:apba1_rat(display_long) uniprotkb:Neuron-specific X11 protein(gene name synonym) uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym) uniprotkb:Adapter protein X11alpha(gene name synonym) uniprotkb:Apba1(gene name) psi-mi:Apba1(display_short) uniprotkb:Mint1(gene name synonym) uniprotkb:X11(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0004"(affinity chromatography technology) |
| First author | Biederer et al. (2002) |
| Identifier of the publication | mint:MINT-5215674 pubmed:12196555 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:10116(rat) taxid:10116("Rattus norvegicus (Rat)") |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-8513501 mint:MINT-59485 |
| Confidence score | intact-miscore:0.40 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:F3D comment:Mutations in both PDZ domains or deletion of both PDZ domains almost completly abolished binding. Together these data suggests that each of the two MINT PDZ domains individually bind to presenilins in vitro comment:homomint comment:mint dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2005/06/29 |
| Update date | 2024/11/14 |
| negative Boolean value | false |
| Feature(s) for interactor A | binding-associated region:456-467(MINT-719582) |
| Feature(s) for interactor B | binding-associated region:670-763(MINT-719574) |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Full identification by DNA sequencing |
| Participant identification method for interactor B | Monoclonal antibody western blot |