Curation Details
Interaction ID: MINT-58323

Unique identifier for interactor Auniprotkb:P29476
Unique identifier for interactor Buniprotkb:P23634
Alternative identifier for interactor Aintact:EBI-349460
uniprotkb:P70594
Alternative identifier for interactor Bintact:EBI-1174388
uniprotkb:B1APW6
uniprotkb:B1APW5
uniprotkb:Q13450
uniprotkb:Q13452
uniprotkb:Q13455
uniprotkb:Q16817
uniprotkb:Q7Z3S1
Aliases for Apsi-mi:nos1_rat(display_long)
uniprotkb:Nos1(gene name)
psi-mi:Nos1(display_short)
uniprotkb:Bnos(gene name synonym)
uniprotkb:NOS type I(gene name synonym)
uniprotkb:Neuronal NOS(gene name synonym)
uniprotkb:Constitutive NOS(gene name synonym)
uniprotkb:NC-NOS(gene name synonym)
uniprotkb:Peptidyl-cysteine S-nitrosylase NOS1(gene name synonym)
uniprotkb:Nitric oxide synthase, brain(gene name synonym)
Aliases for Bpsi-mi:at2b4_human(display_long)
uniprotkb:Plasma membrane calcium ATPase isoform 4(gene name synonym)
uniprotkb:Plasma membrane calcium pump isoform 4(gene name synonym)
uniprotkb:Matrix-remodeling-associated protein 1(gene name synonym)
uniprotkb:ATP2B4(gene name)
psi-mi:ATP2B4(display_short)
uniprotkb:ATP2B2(gene name synonym)
uniprotkb:MXRA1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorSchuh et al. (2001)
Identifier of the publicationpubmed:11591728
mint:MINT-5214668
NCBI Taxonomy identifier for interactor Ataxid:10116(rat)
taxid:10116("Rattus norvegicus (Rat)")
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7999325
mint:MINT-58323
Confidence scoreintact-miscore:0.52
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F1C
comment:"\"Full-length PMCA 4b interacted with purified GST�PDZ fusion protein, directly demonstrating specificity of interaction with the PDZ domain. Similar interaction of PMCA and NOS-I was also observed in extracts of rat brain.

PMCA molecule interacting with NOS-I might reduce the local calcium concentration, leading to reduced activity of NOS-I, a calcium/calmodulin-dependent isoform of NOS; see also PMID: 8530416\""
comment:homomint
comment:mint
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2005/05/06
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Atag:?-?(MINT-592435)
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AMonoclonal antibody western blot
Participant identification method for interactor BMonoclonal antibody western blot