| Unique identifier for interactor A | uniprotkb:P26045 |
| Unique identifier for interactor B | uniprotkb:P78536 |
| Alternative identifier for interactor A | intact:EBI-1047946 uniprotkb:A0AUW9 uniprotkb:E7EN99 uniprotkb:E9PGU7 ensembl:ENSP00000363667.1 |
| Alternative identifier for interactor B | intact:EBI-78188 intact:EBI-28987181 uniprotkb:O60226 ensembl:ENSP00000309968.3 |
| Aliases for A | psi-mi:ptn3_human(display_long) uniprotkb:Protein-tyrosine phosphatase H1(gene name synonym) uniprotkb:PTPN3(gene name) psi-mi:PTPN3(display_short) uniprotkb:PTPH1(gene name synonym) |
| Aliases for B | psi-mi:ada17_human(display_long) uniprotkb:ADAM17(gene name) psi-mi:ADAM17(display_short) uniprotkb:CSVP(gene name synonym) uniprotkb:TACE(gene name synonym) uniprotkb:TNF-alpha-converting enzyme(gene name synonym) uniprotkb:TNF-alpha convertase(gene name synonym) uniprotkb:Snake venom-like protease(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0018"(two hybrid) |
| First author | Zheng et al. (2002) |
| Identifier of the publication | mint:MINT-5215697 pubmed:12207026 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-8519259 mint:MINT-58311 |
| Confidence score | intact-miscore:0.37 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Bait |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:F1 comment:"\"PTPH1 was not able to interact with the cytoplasmic domains of five other ADAMs tested, ADAM9 (MDC9; meltrin ), ADAM10 (MADM; Kuz), ADAM12 (meltrin ), ADAM15 (MDC15; metargidin), and ADAM19 (meltrin ) reported as se�arate entrues in MINT. Thus, PTPH1 does not appear to be a common binding partner of ADAMs, but binds specifically to the cytoplasmic domain of TACE. \"" comment:homomint comment:mint dataset:Virus - Publications including interactions involving viral proteins partial coverage:partial coverage |
| NCBI Taxonomy identifier for the host organism | taxid:559292(yeast) taxid:559292(Saccharomyces cerevisiae) |
| Parameters of the interaction | - |
| Creation date | 2005/05/06 |
| Update date | 2024/11/15 |
| negative Boolean value | false |
| Feature(s) for interactor A | binding-associated region:402-605(MINT-720136) tag:?-?(MINT-720139) |
| Feature(s) for interactor B | mutation decreasing interaction:824-824,822-822(MINT-720148) binding-associated region:820-824(MINT-720145) tag:?-?(MINT-720151) |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Nucleotide sequence identification |
| Participant identification method for interactor B | Nucleotide sequence identification |