| Unique identifier for interactor A | uniprotkb:P27986 |
| Unique identifier for interactor B | uniprotkb:P43405 |
| Alternative identifier for interactor A | intact:EBI-79464 intact:EBI-28974553 uniprotkb:Q15747 uniprotkb:Q4VBZ7 uniprotkb:Q53EM6 uniprotkb:Q8IXA2 uniprotkb:Q8N1C5 uniprotkb:D3DWA0 uniprotkb:B3KT19 uniprotkb:E7EX19 ensembl:ENSP00000428056.1 ensembl:ENSP00000429277.1 ensembl:ENSP00000513316.1 ensembl:ENSP00000513333.1 |
| Alternative identifier for interactor B | intact:EBI-78302 ensembl:ENSP00000364898.1 ensembl:ENSP00000364907.4 |
| Aliases for A | psi-mi:p85a_human(display_long) uniprotkb:PIK3R1(gene name) psi-mi:PIK3R1(display_short) uniprotkb:GRB1(gene name synonym) uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym) |
| Aliases for B | psi-mi:ksyk_human(display_long) uniprotkb:SYK(gene name) psi-mi:SYK(display_short) uniprotkb:Spleen tyrosine kinase(gene name synonym) uniprotkb:p72-Syk(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0018"(two hybrid) |
| First author | Moon et al. (2005) |
| Identifier of the publication | pubmed:15536084 mint:MINT-5217304 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-7375632 mint:MINT-56738 |
| Confidence score | intact-miscore:0.58 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:F4B comment:The C-terminal SH2 domain of p85 does not interact with the kinase domain of Syk, but interacts with a linker region site of phosphorylation comment:homomint comment:mint dataset:Virus - Publications including interactions involving viral proteins |
| NCBI Taxonomy identifier for the host organism | taxid:559292(yeast) taxid:559292(Saccharomyces cerevisiae) |
| Parameters of the interaction | - |
| Creation date | 2005/03/24 |
| Update date | 2024/11/14 |
| negative Boolean value | false |
| Feature(s) for interactor A | tag:?-?(MINT-1210038) binding-associated region:439-724(MINT-1210035) |
| Feature(s) for interactor B | mutation decreasing interaction:396-396(MINT-1210027) binding-associated region:257-363(MINT-1210025) tag:?-?(MINT-1210029) |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Nucleotide sequence identification |
| Participant identification method for interactor B | Nucleotide sequence identification |