Curation Details
Interaction ID: MINT-56693

Unique identifier for interactor Auniprotkb:Q06124
Unique identifier for interactor Buniprotkb:P80200
Alternative identifier for interactor Aintact:EBI-297779
uniprotkb:Q96HD7
uniprotkb:A8K1D9
ensembl:ENSP00000340944.3
intact:EBI-14351608
intact:EBI-11988773
intact:EBI-13004965
Alternative identifier for interactor Bintact:EBI-7130682
intact:MINT-249082
Aliases for Apsi-mi:ptn11_human(display_long)
uniprotkb:PTPN11(gene name)
psi-mi:PTPN11(display_short)
uniprotkb:PTP2C(gene name synonym)
uniprotkb:SHPTP2(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 2C(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1D(gene name synonym)
uniprotkb:SH-PTP3(gene name synonym)
uniprotkb:SH-PTP2(gene name synonym)
Aliases for Bpsi-mi:cga1_helpx(display_long)
uniprotkb:cagA(gene name)
psi-mi:cagA(display_short)
uniprotkb:cai(gene name synonym)
uniprotkb:120 kDa protein(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorHigashi et al. (2002)
Identifier of the publicationpubmed:11743164
mint:MINT-5214933
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:210(helpx)
taxid:210(Helicobacter pylori)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8064792
mint:MINT-56693
Confidence scoreintact-miscore:0.77
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:tyrosine-phosphorylated CagA appears to interact specifically with the SH2 domains of SHP-2
figure legend:F3B F3C
comment:domino
comment:mint
partial coverage:partial coverage
NCBI Taxonomy identifier for the host organismtaxid:9534(chlae-cos_7)
taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)
Parameters of the interaction-
Creation date2002/04/23
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Atag:?-?(MINT-1745225)
binding-associated region:6-216(MINT-1745222)
Feature(s) for interactor Btag:?-?(MINT-1745216)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification