| Unique identifier for interactor A | uniprotkb:Q00987 |
| Unique identifier for interactor B | uniprotkb:P04637 |
| Alternative identifier for interactor A | intact:EBI-389668 intact:EBI-28980679 uniprotkb:A6NL51 uniprotkb:Q13226 uniprotkb:Q13297 uniprotkb:Q13298 uniprotkb:Q13299 uniprotkb:Q13300 uniprotkb:Q13301 uniprotkb:Q53XW0 uniprotkb:Q71TW9 uniprotkb:Q8WYJ1 uniprotkb:Q8WYJ2 uniprotkb:Q9UGI3 uniprotkb:Q9UMT8 uniprotkb:A8K2S6 ensembl:ENSP00000444430.2 |
| Alternative identifier for interactor B | intact:EBI-366083 uniprotkb:Q15086 uniprotkb:Q15087 uniprotkb:Q15088 uniprotkb:Q16535 uniprotkb:Q16807 uniprotkb:Q16808 uniprotkb:Q16809 uniprotkb:Q16810 uniprotkb:Q16811 uniprotkb:Q16848 uniprotkb:Q86UG1 uniprotkb:Q8J016 uniprotkb:Q99659 uniprotkb:Q9BTM4 uniprotkb:Q9HAQ8 uniprotkb:Q9NP68 uniprotkb:Q9NPJ2 uniprotkb:Q9NZD0 uniprotkb:Q9UBI2 uniprotkb:Q9UQ61 intact:EBI-28980681 ensembl:ENSP00000269305.4 ensembl:ENSP00000391478.2 ensembl:ENSP00000424104.2 ensembl:ENSP00000426252.2 uniprotkb:Q2XN98 uniprotkb:Q3LRW1 uniprotkb:Q3LRW2 uniprotkb:Q3LRW3 uniprotkb:Q3LRW4 uniprotkb:Q3LRW5 |
| Aliases for A | psi-mi:mdm2_human(display_long) uniprotkb:MDM2(gene name) psi-mi:MDM2(display_short) uniprotkb:p53-binding protein Mdm2(gene name synonym) uniprotkb:Oncoprotein Mdm2(gene name synonym) uniprotkb:Double minute 2 protein(gene name synonym) uniprotkb:RING-type E3 ubiquitin transferase Mdm2(gene name synonym) |
| Aliases for B | psi-mi:p53_human(display_long) uniprotkb:TP53(gene name) psi-mi:TP53(display_short) uniprotkb:P53(gene name synonym) uniprotkb:Tumor suppressor p53(gene name synonym) uniprotkb:Phosphoprotein p53(gene name synonym) uniprotkb:Antigen NY-CO-13(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0107"(surface plasmon resonance) |
| First author | Vassilev et al. (2004) |
| Identifier of the publication | pubmed:14704432 mint:MINT-5216851 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-7085448 mint:MINT-56681 |
| Confidence score | intact-miscore:0.99 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Bait |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:F1A comment:Cis-imidazoline analogs named Nutlins inhibits MDM2-p53 binding kinetics:IC50 = 100-300 nanomolar comment:homomint comment:mint dataset:Virus - Publications including interactions involving viral proteins |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2005/03/21 |
| Update date | 2024/09/10 |
| negative Boolean value | false |
| Feature(s) for interactor A | binding-associated region:25-108(MINT-1130295) tag:?-?(MINT-1130298) |
| Feature(s) for interactor B | binding-associated region:1-312(MINT-1130287) tag:?-?(MINT-1130289) |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Nucleotide sequence identification |
| Participant identification method for interactor B | Nucleotide sequence identification |