Curation Details
Interaction ID: MINT-56652

Unique identifier for interactor Auniprotkb:P04629-2
Unique identifier for interactor Buniprotkb:P29350
Alternative identifier for interactor Aintact:EBI-7399529
intact:MINT-124142
ensembl:ENSP00000357179.3
Alternative identifier for interactor Bintact:EBI-78260
uniprotkb:A8K306
uniprotkb:G3V0F8
uniprotkb:Q9UK67
ensembl:ENSP00000326010.9
intact:EBI-28977917
uniprotkb:Q969V8
Aliases for Apsi-mi:p04629-2(display_long)
uniprotkb:NTRK1(gene name)
psi-mi:NTRK1(display_short)
uniprotkb:MTC(gene name synonym)
uniprotkb:Neurotrophic tyrosine kinase receptor type 1(gene name synonym)
uniprotkb:TRK(gene name synonym)
uniprotkb:TRK1-transforming tyrosine kinase protein(gene name synonym)
uniprotkb:TRKA(gene name synonym)
uniprotkb:Tropomyosin-related kinase A(gene name synonym)
uniprotkb:Tyrosine kinase receptor(gene name synonym)
uniprotkb:Tyrosine kinase receptor A(gene name synonym)
uniprotkb:gp140trk(gene name synonym)
uniprotkb:p140-TrkA(gene name synonym)
uniprotkb:TrkAI(isoform synonym)
Aliases for Bpsi-mi:ptn6_human(display_long)
uniprotkb:PTPN6(gene name)
psi-mi:PTPN6(display_short)
uniprotkb:HCP(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)
uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)
uniprotkb:SH-PTP1(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase SHP-1(gene name synonym)
uniprotkb:PTP1C(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorRoccato et al. (2005)
Identifier of the publicationpubmed:15557341
mint:MINT-5217351
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7399523
mint:MINT-56652
Confidence scoreintact-miscore:0.40
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F1B
comment:Protein A is the TRK-T3 oncoprotein which consists of the NTRK1 tyrosine kinase domain fused in frame with sequences of the TFG. Since such protein is not present in Uniprot we use dthe Swiss prot of the NTRK1 protein
comment:homomint
comment:mint
partial coverage:partial coverage
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293t)
taxid:9606(Homo sapiens HEK293T embryonic kidney cell)
Parameters of the interaction-
Creation date2005/03/16
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AMonoclonal antibody western blot
Participant identification method for interactor BNucleotide sequence identification