| Unique identifier for interactor A | uniprotkb:P16104 |
| Unique identifier for interactor B | uniprotkb:Q14191 |
| Alternative identifier for interactor A | intact:EBI-494830 uniprotkb:Q4ZGJ7 uniprotkb:Q6IAS5 ensembl:ENSP00000364310.1 ensembl:ENSP00000434024.1 |
| Alternative identifier for interactor B | intact:EBI-368417 ensembl:ENSP00000298139.5 uniprotkb:A1KYY9 |
| Aliases for A | psi-mi:h2ax_human(display_long) uniprotkb:H2AX(gene name) psi-mi:H2AX(display_short) uniprotkb:H2AFX(gene name synonym) uniprotkb:Histone H2A.X(gene name synonym) |
| Aliases for B | psi-mi:wrn_human(display_long) uniprotkb:WRN(gene name) psi-mi:WRN(display_short) uniprotkb:RECQ3(gene name synonym) uniprotkb:RECQL2(gene name synonym) uniprotkb:RecQ protein-like 2(gene name synonym) uniprotkb:DNA helicase, RecQ-like type 3(gene name synonym) uniprotkb:Werner syndrome protein(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0416"(fluorescence microscopy) |
| First author | Cheng et al. (2005) |
| Identifier of the publication | pubmed:15733840 imex:IM-10848 mint:MINT-5217546 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0403"(colocalization) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-7492599 mint:MINT-56619 imex:IM-10848-2 |
| Confidence score | intact-miscore:0.67 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Bait |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:F2 comment:SHOTLABEL=NBS cells. The interaction occurs in the insoluble fraction and after 3 hours of gamma-irradiation. The WRN association with H2AX depends upon Nbs1 expression and Nbs1 Ser-343 phosphorylation comment:homomint comment:mint dataset:Virus - Publications including interactions involving viral proteins full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-mrc5) taxid:9606(Homo sapiens MRC-5 diploid foetal lung fibroblast-like cell) |
| Parameters of the interaction | - |
| Creation date | 2005/03/15 |
| Update date | 2014/10/16 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Monoclonal antibody western blot |
| Participant identification method for interactor B | Monoclonal antibody western blot |