Curation Details
Interaction ID: MINT-5224259

Unique identifier for interactor Auniprotkb:P04271
Unique identifier for interactor Buniprotkb:Q15109
Alternative identifier for interactor Aintact:EBI-458391
uniprotkb:D3DSN6
ensembl:ENSP00000291700.4
ensembl:ENSP00000380769.1
Alternative identifier for interactor Bintact:EBI-1646426
uniprotkb:V5R6A3
uniprotkb:Q3L1S0
uniprotkb:A2BFI7
intact:EBI-3959557
uniprotkb:A6NKF0
uniprotkb:Q86SN1
uniprotkb:Q3L1R7
uniprotkb:A7Y2U9
uniprotkb:Q3L1R4
uniprotkb:Q3L1R5
uniprotkb:Q3L1R6
uniprotkb:Q3L1R8
ensembl:ENSP00000364217.4
ensembl:ENSP00000395812.2
ensembl:ENSP00000397227.2
ensembl:ENSP00000401068.2
ensembl:ENSP00000409457.2
ensembl:ENSP00000415144.2
ensembl:ENSP00000416042.2
uniprotkb:B0V176
uniprotkb:Q15279
uniprotkb:Q9H2X7
uniprotkb:Q9Y3R3
Aliases for Apsi-mi:s100b_human(display_long)
uniprotkb:S100B(gene name)
psi-mi:S100B(display_short)
uniprotkb:S100 calcium-binding protein B(gene name synonym)
uniprotkb:S-100 protein subunit beta(gene name synonym)
uniprotkb:S-100 protein beta chain(gene name synonym)
Aliases for Bpsi-mi:rage_human(display_long)
uniprotkb:AGER(gene name)
psi-mi:AGER(display_short)
uniprotkb:RAGE(gene name synonym)
uniprotkb:Receptor for advanced glycosylation end products(gene name synonym)
Interaction detection methodspsi-mi:"MI:0107"(surface plasmon resonance)
First authorOstendorp et al. (2007)
Identifier of the publicationpubmed:17660747
imex:IM-11229
mint:MINT-5223994
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7513324
mint:MINT-5224259
imex:IM-11229-13
Confidence scoreintact-miscore:0.72
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f6a
kinetics:kd 8.3 micromolar
comment:Dimeric form of S100B links Rage with a Kd of 8.3 micromolar.
comment:homomint
comment:mint
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2007/11/23
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bglutathione s tranferase tag:?-?(MINT-5224264)
binding-associated region:23-322(MINT-5224262)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant