Curation Details
Interaction ID: MINT-51643

Unique identifier for interactor Aintact:EBI-7463640
Unique identifier for interactor Buniprotkb:Q01094
Alternative identifier for interactor Aintact:MINT-137136
Alternative identifier for interactor Bintact:EBI-448924
ensembl:ENSP00000345571.5
uniprotkb:Q13143
uniprotkb:Q92768
Aliases for Apsi-mi:q92722(display_short)
psi-mi:EBI-7463640(display_long)
Aliases for Bpsi-mi:e2f1_human(display_long)
uniprotkb:Retinoblastoma-associated protein 1(gene name synonym)
uniprotkb:Retinoblastoma-binding protein 3(gene name synonym)
uniprotkb:PBR3(gene name synonym)
uniprotkb:E2F1(gene name)
psi-mi:E2F1(display_short)
uniprotkb:RBBP3(gene name synonym)
uniprotkb:pRB-binding protein E2F-1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorDe et al. (2005)
Identifier of the publicationpubmed:15670817
imex:IM-10874
mint:MINT-5217483
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7463647
mint:MINT-51643
imex:IM-10874-1
Confidence scoreintact-miscore:0.40
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F3B
comment:SHORT LABEL=MG63 cells.

3-AB treatment induces the production of the hypophosphorylated/active status of Rb and increases the levels of pRb/E2F complex
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-4(in vivo)
taxid:-4(in vivo)
Parameters of the interaction-
Creation date2005/03/08
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AMonoclonal antibody western blot
Participant identification method for interactor BMonoclonal antibody western blot