Curation Details
Interaction ID: MINT-51491

Unique identifier for interactor Auniprotkb:P25098
Unique identifier for interactor Buniprotkb:P00533
Alternative identifier for interactor Aintact:EBI-3904795
uniprotkb:Q6GTT3
uniprotkb:B0ZBE1
uniprotkb:Q13837
ensembl:ENSP00000312262.5
Alternative identifier for interactor Bintact:EBI-297353
uniprotkb:Q9BZS2
uniprotkb:Q9GZX1
uniprotkb:Q9H2C9
uniprotkb:Q9H3C9
uniprotkb:Q9UMD7
uniprotkb:Q9UMD8
uniprotkb:Q9UMG5
uniprotkb:O00688
uniprotkb:O00732
uniprotkb:P06268
uniprotkb:Q14225
uniprotkb:Q92795
intact:EBI-28985169
uniprotkb:Q68GS5
ensembl:ENSP00000275493.2
Aliases for Apsi-mi:arbk1_human(display_long)
uniprotkb:GRK2(gene name)
psi-mi:GRK2(display_short)
uniprotkb:ADRBK1(gene name synonym)
uniprotkb:BARK(gene name synonym)
uniprotkb:BARK1(gene name synonym)
uniprotkb:G-protein coupled receptor kinase 2(gene name synonym)
Aliases for Bpsi-mi:egfr_human(display_long)
uniprotkb:ERBB1(gene name synonym)
uniprotkb:EGFR(gene name)
psi-mi:EGFR(display_short)
uniprotkb:Receptor tyrosine-protein kinase erbB-1(gene name synonym)
uniprotkb:Proto-oncogene c-ErbB-1(gene name synonym)
uniprotkb:ERBB(gene name synonym)
uniprotkb:HER1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorGao et al. (2005)
Identifier of the publicationpubmed:15620700
mint:MINT-5217433
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7436130
mint:MINT-51491
Confidence scoreintact-miscore:0.46
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F1B
comment:The formation of the GRK2-EGFR complex after EGF subministration is time dependent
comment:homomint
comment:mint
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293)
taxid:9606(Homo sapiens HEK293 embryonic kidney cell)
Parameters of the interaction-
Creation date2005/03/02
Update date2024/09/10
negative Boolean valuefalse
Feature(s) for interactor Atag:?-?(MINT-1214697)
Feature(s) for interactor Btag:?-?(MINT-1214691)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AMonoclonal antibody western blot
Participant identification method for interactor BNucleotide sequence identification