Curation Details
Interaction ID: MINT-50715

Unique identifier for interactor Auniprotkb:P22681
Unique identifier for interactor Buniprotkb:P43405
Alternative identifier for interactor Aintact:EBI-518228
uniprotkb:A3KMP8
ensembl:ENSP00000264033.3
Alternative identifier for interactor Bintact:EBI-78302
ensembl:ENSP00000364898.1
ensembl:ENSP00000364907.4
Aliases for Apsi-mi:cbl_human(display_long)
uniprotkb:Signal transduction protein CBL(gene name synonym)
uniprotkb:Proto-oncogene c-Cbl(gene name synonym)
uniprotkb:Casitas B-lineage lymphoma proto-oncogene(gene name synonym)
uniprotkb:RING finger protein 55(gene name synonym)
uniprotkb:CBL(gene name)
psi-mi:CBL(display_short)
uniprotkb:CBL2(gene name synonym)
uniprotkb:RNF55(gene name synonym)
uniprotkb:RING-type E3 ubiquitin transferase CBL(gene name synonym)
Aliases for Bpsi-mi:ksyk_human(display_long)
uniprotkb:SYK(gene name)
psi-mi:SYK(display_short)
uniprotkb:Spleen tyrosine kinase(gene name synonym)
uniprotkb:p72-Syk(gene name synonym)
Interaction detection methodspsi-mi:"MI:0045"(experimental interaction detection)
First authorGrossmann et al. (2004)
Identifier of the publicationpubmed:15556646
mint:MINT-5217342
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0217"(phosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7391948
mint:MINT-50715
Confidence scoreintact-miscore:0.74
Complex expansion-
Biological role AEnzyme target
Biological role BEnzyme
Experimental role AUnspecified role
Experimental role BUnspecified role
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F1A F1B
comment:the modifications of c-Cbl refer to the Y phosphorylated by SYK in this experiment
comment:homomint
comment:domino
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
partial coverage:partial coverage
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2004/12/10
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor AO4'-phospho-L-tyrosine:731-731(MINT-1210922)
tag:?-?(MINT-1210926)
O4'-phospho-L-tyrosine:700-700(MINT-1210920)
binding-associated region:542-906(MINT-1210917)
O4'-phospho-L-tyrosine:774-774(MINT-1210924)
Feature(s) for interactor Bbinding-associated region:370-626(MINT-1210933)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification