| Unique identifier for interactor A | uniprotkb:P38936 |
| Unique identifier for interactor B | uniprotkb:P14635 |
| Alternative identifier for interactor A | intact:EBI-375077 uniprotkb:Q14010 uniprotkb:Q9BUT4 uniprotkb:Q6FI05 ensembl:ENSP00000244741.6 ensembl:ENSP00000362815.1 ensembl:ENSP00000384849.1 ensembl:ENSP00000409259.3 ensembl:ENSP00000482768.1 |
| Alternative identifier for interactor B | intact:EBI-495332 uniprotkb:A8K066 uniprotkb:Q5TZP9 ensembl:ENSP00000256442.5 |
| Aliases for A | psi-mi:cdn1a_human(display_long) uniprotkb:CDKN1A(gene name) psi-mi:CDKN1A(display_short) uniprotkb:CAP20(gene name synonym) uniprotkb:CDKN1(gene name synonym) uniprotkb:CIP1(gene name synonym) uniprotkb:MDA6(gene name synonym) uniprotkb:PIC1(gene name synonym) uniprotkb:SDI1(gene name synonym) uniprotkb:WAF1(gene name synonym) uniprotkb:p21(gene name synonym) uniprotkb:CDK-interacting protein 1(gene name synonym) uniprotkb:Melanoma differentiation-associated protein 6(gene name synonym) |
| Aliases for B | psi-mi:ccnb1_human(display_long) uniprotkb:CCNB1(gene name) psi-mi:CCNB1(display_short) uniprotkb:CCNB(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0019"(coimmunoprecipitation) |
| First author | Zhang et al. (2004) |
| Identifier of the publication | pubmed:15251430 mint:MINT-5217105 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-7273709 mint:MINT-50660 |
| Confidence score | intact-miscore:0.73 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | comment:"\"In mint_50659, ING4 is reported to associate physically with p53. In other experiments in the same paper the ING4-induced expression of some genes involved in cell cycle and apoptosis in the derived HepG2 cell clones is monitored by Northern blot analysis.It is shown that upregulation of p21 seems to parallel with level of ING4. ING4-induced upregulation of p21 could strengthen the association of cyclin B1 and p21, which may contribute to the G2/m arrest in the HepG2 cells(mint_50660)\"" figure legend:F4D comment:homomint comment:mint dataset:Virus - Publications including interactions involving viral proteins |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-hep_g2) taxid:9606(Homo sapiens HepG2 hepatocellular carcinoma cell) |
| Parameters of the interaction | - |
| Creation date | 2004/12/03 |
| Update date | 2024/11/14 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Monoclonal antibody western blot |
| Participant identification method for interactor B | Nucleotide sequence identification |