Curation Details
Interaction ID: MINT-50107

Unique identifier for interactor Auniprotkb:O14920
Unique identifier for interactor Buniprotkb:Q04206
Alternative identifier for interactor Aintact:EBI-81266
ensembl:ENSP00000430684.1
uniprotkb:O75327
uniprotkb:B4E0U4
uniprotkb:B4DZ30
Alternative identifier for interactor Bintact:EBI-73886
ensembl:ENSP00000384273.3
uniprotkb:Q6GTV1
uniprotkb:Q6SLK1
Aliases for Apsi-mi:ikkb_human(display_long)
uniprotkb:IKBKB(gene name)
psi-mi:IKBKB(display_short)
uniprotkb:IKKB(gene name synonym)
uniprotkb:I-kappa-B kinase 2(gene name synonym)
uniprotkb:Nuclear factor NF-kappa-B inhibitor kinase beta(gene name synonym)
uniprotkb:Serine/threonine protein kinase IKBKB(gene name synonym)
Aliases for Bpsi-mi:tf65_human(display_long)
uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)
uniprotkb:RELA(gene name)
psi-mi:RELA(display_short)
uniprotkb:NFKB3(gene name synonym)
uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)
Interaction detection methodspsi-mi:"MI:0424"(protein kinase assay)
First authorSakurai et al. (2003)
Identifier of the publicationpubmed:12842894
mint:MINT-5216511
imex:IM-27286
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0217"(phosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-6959797
mint:MINT-50107
imex:IM-27286-1
Confidence scoreintact-miscore:0.68
Complex expansion-
Biological role AEnzyme
Biological role BEnzyme target
Experimental role AUnspecified role
Experimental role BUnspecified role
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:Fig. 7
resulting-ptm:Q04206 O-phospho-L-serine ser-536
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2004/07/26
Update date2015/08/04
negative Boolean valuefalse
Feature(s) for interactor Ahis tag:?-?(MINT-736657)
Feature(s) for interactor Bglutathione s tranferase tag:?-?(MINT-736664)
sufficient binding region:354-551
O-phospho-L-serine:536-536
mutation decreasing interaction rate:536-536
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BMonoclonal antibody western blot