Curation Details
Interaction ID: MINT-50072

Unique identifier for interactor Auniprotkb:P22681
Unique identifier for interactor Buniprotkb:P07949
Alternative identifier for interactor Aintact:EBI-518228
ensembl:ENSP00000264033.3
uniprotkb:A3KMP8
Alternative identifier for interactor Bintact:EBI-2480756
intact:EBI-28967738
uniprotkb:A8K6Z2
uniprotkb:Q9BTB0
uniprotkb:Q15250
uniprotkb:Q9H4A2
ensembl:ENSP00000347942.3
Aliases for Apsi-mi:cbl_human(display_long)
uniprotkb:Signal transduction protein CBL(gene name synonym)
uniprotkb:Proto-oncogene c-Cbl(gene name synonym)
uniprotkb:Casitas B-lineage lymphoma proto-oncogene(gene name synonym)
uniprotkb:RING finger protein 55(gene name synonym)
uniprotkb:CBL(gene name)
psi-mi:CBL(display_short)
uniprotkb:CBL2(gene name synonym)
uniprotkb:RNF55(gene name synonym)
uniprotkb:RING-type E3 ubiquitin transferase CBL(gene name synonym)
Aliases for Bpsi-mi:ret_human(display_long)
uniprotkb:RET(gene name)
psi-mi:RET(display_short)
uniprotkb:CDHF12(gene name synonym)
uniprotkb:Cadherin family member 12(gene name synonym)
uniprotkb:Proto-oncogene c-Ret(gene name synonym)
uniprotkb:CDHR16(gene name synonym)
uniprotkb:PTC(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorCarniti et al. (2003)
Identifier of the publicationmint:MINT-5216347
pubmed:12727845
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8640972
mint:MINT-50072
Confidence scoreintact-miscore:0.70
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:"\"This experiment was done using the mutants: Cys634 changed into Arg (TGC to CGC) and Met918 changed into Thr (ATG to ACG), the presence of PPI (pyrazolo-pyrimidine inhibitor) did not affect the interaction and both mutants can be ubiquitinated.\""
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
NCBI Taxonomy identifier for the host organismtaxid:-4(in vivo)
taxid:-4(in vivo)
Parameters of the interaction-
Creation date2004/07/14
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AMonoclonal antibody western blot
Participant identification method for interactor BMonoclonal antibody western blot