Unique identifier for interactor A | uniprotkb:P11716 |
Unique identifier for interactor B | uniprotkb:P62942 |
Alternative identifier for interactor A | intact:EBI-6477441 |
Alternative identifier for interactor B | intact:EBI-1027571 uniprotkb:P20071 uniprotkb:Q4VC47 uniprotkb:Q6FGD9 uniprotkb:Q6LEU3 uniprotkb:Q9H103 uniprotkb:Q9H566 uniprotkb:D3DVW6 ensembl:ENSP00000371138.3 ensembl:ENSP00000371143.4 ensembl:ENSP00000383003.4 ensembl:ENSP00000503033.1 ensembl:ENSP00000503152.1 |
Aliases for A | psi-mi:ryr1_rabit(display_long) uniprotkb:RYR1(gene name) psi-mi:RYR1(display_short) uniprotkb:Skeletal muscle calcium release channel(gene name synonym) uniprotkb:Skeletal muscle ryanodine receptor(gene name synonym) uniprotkb:Skeletal muscle-type ryanodine receptor(gene name synonym) uniprotkb:Type 1 ryanodine receptor(gene name synonym) |
Aliases for B | psi-mi:fkb1a_human(display_long) uniprotkb:FKBP1A(gene name) psi-mi:FKBP1A(display_short) uniprotkb:FKBP1(gene name synonym) uniprotkb:FKBP12(gene name synonym) uniprotkb:FK506-binding protein 1A(gene name synonym) uniprotkb:Rotamase(gene name synonym) uniprotkb:Immunophilin FKBP12(gene name synonym) uniprotkb:12 kDa FK506-binding protein(gene name synonym) uniprotkb:Calstabin-1(gene name synonym) |
Interaction detection methods | psi-mi:"MI:0004"(affinity chromatography technology) |
First author | Bultynck et al. (2001) |
Identifier of the publication | pubmed:11171121 mint:MINT-5213503 |
NCBI Taxonomy identifier for interactor A | taxid:9986(rabit) taxid:9986("Oryctolagus cuniculus (Rabbit)") |
NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
Interaction types | psi-mi:"MI:0915"(physical association) |
Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
Interaction identifier(s) in the corresponding source database | intact:EBI-7487780 mint:MINT-49708 |
Confidence score | intact-miscore:0.70 |
Complex expansion | - |
Biological role A | Unspecified role |
Biological role B | Unspecified role |
Experimental role A | Prey |
Experimental role B | Bait |
Interactor type A | Protein |
Interactor type B | Protein |
Annotations for the interaction | comment:"\"To identify the domain that is necessary and sufficient for FKBP12 binding, the authors performed GST-FKBP12 affinity chromatography on partially trypsinized RyR1 and IP3R1. The proposed range of interaction for Ryr1(2461-2803) in MINT database comes from the joining of the information about the epitope recognised by m34C (amino acids 2756�2803) and the information about the putative FKBP12-binding site based on the analogy with the FKBP12-binding site proposed for IP3R1 (the putative FKBP12-binding site is localized in the proximity of amino acids 2461�2462)\"" comment:mint dataset:Virus - Publications including interactions involving viral proteins |
NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
Parameters of the interaction | - |
Creation date | 2004/04/27 |
Update date | 2024/09/10 |
negative Boolean value | false |
Feature(s) for interactor A | binding-associated region:2461-2803(MINT-445164) |
Feature(s) for interactor B | tag:?-?(MINT-445158) |
Stoichiometry for interactor A | - |
Stoichiometry for interactor B | - |
Participant identification method for interactor A | Monoclonal antibody western blot |
Participant identification method for interactor B | Nucleotide sequence identification |