| Unique identifier for interactor A | uniprotkb:P29353 |
| Unique identifier for interactor B | uniprotkb:P05067 |
| Alternative identifier for interactor A | intact:EBI-78835 uniprotkb:O15290 uniprotkb:Q5T180 uniprotkb:Q5T183 uniprotkb:Q5T184 uniprotkb:Q5T185 uniprotkb:Q5T186 uniprotkb:Q8N4K5 uniprotkb:Q96CL1 uniprotkb:B5BU19 uniprotkb:D3DV78 ensembl:ENSP00000357430.5 |
| Alternative identifier for interactor B | intact:EBI-77613 uniprotkb:P09000 uniprotkb:P78438 uniprotkb:Q13764 uniprotkb:Q13778 uniprotkb:Q13793 intact:EBI-28985182 uniprotkb:Q6GSC0 uniprotkb:Q8WZ99 uniprotkb:Q9UC33 uniprotkb:Q9UCC8 uniprotkb:Q9UCD1 uniprotkb:Q9UQ58 uniprotkb:Q16011 uniprotkb:Q16014 uniprotkb:Q16019 uniprotkb:Q16020 uniprotkb:Q9BT38 uniprotkb:Q9UCA9 uniprotkb:Q9UCB6 uniprotkb:B4DII8 uniprotkb:B2R5V1 uniprotkb:D3DSD1 uniprotkb:D3DSD2 uniprotkb:D3DSD3 ensembl:ENSP00000284981.4 |
| Aliases for A | psi-mi:shc1_human(display_long) uniprotkb:SHC1(gene name) psi-mi:SHC1(display_short) uniprotkb:SHC(gene name synonym) uniprotkb:SHCA(gene name synonym) uniprotkb:Src homology 2 domain-containing-transforming protein C1(gene name synonym) uniprotkb:SHC-transforming protein A(gene name synonym) uniprotkb:SHC-transforming protein 3(gene name synonym) |
| Aliases for B | psi-mi:a4_human(display_long) uniprotkb:APP(gene name) psi-mi:APP(display_short) uniprotkb:A4(gene name synonym) uniprotkb:AD1(gene name synonym) uniprotkb:Alzheimer disease amyloid protein(gene name synonym) uniprotkb:ABPP(gene name synonym) uniprotkb:PreA4(gene name synonym) uniprotkb:Cerebral vascular amyloid peptide(gene name synonym) uniprotkb:Protease nexin-II(gene name synonym) uniprotkb:APPI(gene name synonym) uniprotkb:Amyloid precursor protein(gene name synonym) uniprotkb:Amyloid-beta A4 protein(gene name synonym) uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym) uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0019"(coimmunoprecipitation) |
| First author | Russo et al. (2002) |
| Identifier of the publication | mint:MINT-5215996 pubmed:12485888 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-8577634 mint:MINT-49660 |
| Confidence score | intact-miscore:0.59 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | comment:"\"Although Shc A precipitated in both thrombin-treated and untreated cells, after thrombin activation do Shc and TYR-phosphorylated CTFs (APP) interact.\"" comment:homomint comment:mint dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease dataset:Virus - Publications including interactions involving viral proteins |
| NCBI Taxonomy identifier for the host organism | taxid:-4(in vivo) taxid:-4(in vivo) |
| Parameters of the interaction | - |
| Creation date | 2004/04/15 |
| Update date | 2024/11/12 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | O4'-phospho-L-tyrosine:682-682(MINT-725528) |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Monoclonal antibody western blot |
| Participant identification method for interactor B | Monoclonal antibody western blot |