Unique identifier for interactor A | uniprotkb:O60934 |
Unique identifier for interactor B | uniprotkb:O96017 |
Alternative identifier for interactor A | intact:EBI-494844 uniprotkb:B2R626 uniprotkb:B2RNC5 ensembl:ENSP00000265433.4 ensembl:ENSP00000513229.1 ensembl:ENSP00000513245.1 uniprotkb:O60672 uniprotkb:Q32NF7 uniprotkb:Q53FM6 uniprotkb:Q63HR6 uniprotkb:Q7LDM2 |
Alternative identifier for interactor B | intact:EBI-1180783 uniprotkb:B7ZBF3 uniprotkb:B7ZBF4 uniprotkb:B7ZBF5 uniprotkb:Q9HBS5 uniprotkb:A8K3Y9 ensembl:ENSP00000385747.1 ensembl:ENSP00000386087.1 ensembl:ENSP00000497000.1 uniprotkb:Q6QA03 uniprotkb:Q6QA04 uniprotkb:Q6QA05 uniprotkb:Q6QA06 uniprotkb:Q6QA07 uniprotkb:Q6QA08 uniprotkb:Q6QA10 uniprotkb:Q6QA11 uniprotkb:Q6QA12 uniprotkb:Q6QA13 uniprotkb:Q9HCQ8 uniprotkb:Q9UGF0 uniprotkb:Q9UGF1 |
Aliases for A | psi-mi:nbn_human(display_long) uniprotkb:Nijmegen breakage syndrome protein 1(gene name synonym) uniprotkb:Cell cycle regulatory protein p95(gene name synonym) uniprotkb:NBN(gene name) psi-mi:NBN(display_short) uniprotkb:NBS1(gene name synonym) uniprotkb:NBS(gene name synonym) uniprotkb:P95(gene name synonym) |
Aliases for B | psi-mi:chk2_human(display_long) uniprotkb:CHEK2(gene name) psi-mi:CHEK2(display_short) uniprotkb:CHK2(gene name synonym) uniprotkb:RAD53(gene name synonym) uniprotkb:Cds1 homolog(gene name synonym) uniprotkb:Checkpoint kinase 2(gene name synonym) uniprotkb:CDS1(gene name synonym) uniprotkb:CHK2 checkpoint homolog(gene name synonym) |
Interaction detection methods | psi-mi:"MI:0045"(experimental interaction detection) |
First author | Buscemi et al. (2001) |
Identifier of the publication | pubmed:11438675 mint:MINT-5214232 doi:10.1128/MCB.21.15.5214-5222.2001 |
NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
Interaction types | psi-mi:"MI:0217"(phosphorylation reaction) |
Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
Interaction identifier(s) in the corresponding source database | intact:EBI-7898191 mint:MINT-49650 |
Confidence score | intact-miscore:0.40 |
Complex expansion | - |
Biological role A | Unspecified role |
Biological role B | Unspecified role |
Experimental role A | Unspecified role |
Experimental role B | Unspecified role |
Interactor type A | Protein |
Interactor type B | Protein |
Annotations for the interaction | comment:Chk2 needs the presence of Nbs1 to be phosphorylated and activated after the induction of DNA damage comment:homomint comment:mint |
NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
Parameters of the interaction | - |
Creation date | 2004/04/15 |
Update date | 2014/10/16 |
negative Boolean value | false |
Feature(s) for interactor A | mutation decreasing interaction:343-343,590-590(MINT-580435) |
Feature(s) for interactor B | - |
Stoichiometry for interactor A | - |
Stoichiometry for interactor B | - |
Participant identification method for interactor A | Monoclonal antibody western blot |
Participant identification method for interactor B | Monoclonal antibody western blot |