| Unique identifier for interactor A | uniprotkb:P29353 |
| Unique identifier for interactor B | uniprotkb:P33151 |
| Alternative identifier for interactor A | intact:EBI-78835 uniprotkb:O15290 uniprotkb:Q5T180 uniprotkb:Q5T183 uniprotkb:Q5T184 uniprotkb:Q5T185 uniprotkb:Q5T186 uniprotkb:Q8N4K5 uniprotkb:Q96CL1 uniprotkb:B5BU19 ensembl:ENSP00000357430.5 uniprotkb:D3DV78 |
| Alternative identifier for interactor B | intact:EBI-2903122 uniprotkb:Q4VAI5 uniprotkb:Q4VAI6 ensembl:ENSP00000344115.3 ensembl:ENSP00000497290.1 |
| Aliases for A | psi-mi:shc1_human(display_long) uniprotkb:SHC1(gene name) psi-mi:SHC1(display_short) uniprotkb:SHC(gene name synonym) uniprotkb:SHCA(gene name synonym) uniprotkb:Src homology 2 domain-containing-transforming protein C1(gene name synonym) uniprotkb:SHC-transforming protein A(gene name synonym) uniprotkb:SHC-transforming protein 3(gene name synonym) |
| Aliases for B | psi-mi:cadh5_human(display_long) uniprotkb:CDH5(gene name) psi-mi:CDH5(display_short) uniprotkb:Vascular endothelial cadherin(gene name synonym) uniprotkb:7B4 antigen(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0096"(pull down) |
| First author | Zanetti et al. (2002) |
| Identifier of the publication | pubmed:11950700 mint:MINT-5215280 doi:10.1161/01.ATV.0000012268.84961.AD |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-8298601 mint:MINT-49636 |
| Confidence score | intact-miscore:0.54 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | comment:"\"This interaction is of particular importance because: 1) it masks the cadherin/beta-catenin binding 2) a phosphatase associated to cadherin dephosphorilates SHC. 3)Other domains (i.e.PTB e CHI) do not bind to either interactors when the latest are phosphorylated.\"" comment:homomint comment:mint |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2004/04/10 |
| Update date | 2025/08/11 |
| negative Boolean value | false |
| Feature(s) for interactor A | binding-associated region:488-579(MINT-713849) tag:?-?(MINT-713852) |
| Feature(s) for interactor B | binding-associated region:702-784(MINT-713842) |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Nucleotide sequence identification |
| Participant identification method for interactor B | Monoclonal antibody western blot |