Curation Details
Interaction ID: MINT-3974360

Unique identifier for interactor Auniprotkb:P07339
Unique identifier for interactor Buniprotkb:P05067
Alternative identifier for interactor Aintact:EBI-2115097
uniprotkb:Q6IB57
ensembl:ENSP00000236671.2
Alternative identifier for interactor Bintact:EBI-77613
uniprotkb:P09000
uniprotkb:P78438
uniprotkb:Q13764
uniprotkb:Q13778
uniprotkb:Q13793
intact:EBI-28985182
uniprotkb:Q6GSC0
uniprotkb:Q8WZ99
uniprotkb:Q9UC33
uniprotkb:Q9UCC8
uniprotkb:Q9UCD1
uniprotkb:Q9UQ58
uniprotkb:Q16011
uniprotkb:Q16014
uniprotkb:Q16019
uniprotkb:Q16020
uniprotkb:Q9BT38
uniprotkb:Q9UCA9
uniprotkb:Q9UCB6
uniprotkb:B4DII8
ensembl:ENSP00000284981.4
uniprotkb:B2R5V1
uniprotkb:D3DSD1
uniprotkb:D3DSD2
uniprotkb:D3DSD3
Aliases for Apsi-mi:catd_human(display_long)
uniprotkb:CTSD(gene name)
psi-mi:CTSD(display_short)
uniprotkb:CPSD(gene name synonym)
Aliases for Bpsi-mi:a4_human(display_long)
uniprotkb:APP(gene name)
psi-mi:APP(display_short)
uniprotkb:A4(gene name synonym)
uniprotkb:AD1(gene name synonym)
uniprotkb:Alzheimer disease amyloid protein(gene name synonym)
uniprotkb:ABPP(gene name synonym)
uniprotkb:PreA4(gene name synonym)
uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)
uniprotkb:Protease nexin-II(gene name synonym)
uniprotkb:APPI(gene name synonym)
uniprotkb:Amyloid precursor protein(gene name synonym)
uniprotkb:Amyloid-beta A4 protein(gene name synonym)
uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)
uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)
Interaction detection methodspsi-mi:"MI:0435"(protease assay)
First authorSakamoto et al. (2006)
Identifier of the publicationpubmed:17112520
imex:IM-11295
mint:MINT-5219353
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0194"(cleavage reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7103740
mint:MINT-3974360
imex:IM-11295-2
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AEnzyme
Biological role BEnzyme target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F3
comment:homomint
comment:mint
dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2006/12/18
Update date2024/09/11
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bbinding-associated region:1-40(MINT-3974371)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification