Curation Details
Interaction ID: MINT-3974318

Unique identifier for interactor Auniprotkb:P07858
Unique identifier for interactor Buniprotkb:Q9NYA1
Alternative identifier for interactor Aintact:EBI-715062
uniprotkb:Q503A6
uniprotkb:Q96D87
uniprotkb:B3KRR5
uniprotkb:B3KQR5
ensembl:ENSP00000342070.3
ensembl:ENSP00000345672.5
ensembl:ENSP00000431143.2
ensembl:ENSP00000431518.2
ensembl:ENSP00000432244.1
ensembl:ENSP00000432408.2
ensembl:ENSP00000433215.1
ensembl:ENSP00000433379.3
ensembl:ENSP00000433929.2
ensembl:ENSP00000434217.1
ensembl:ENSP00000434725.2
ensembl:ENSP00000435074.2
ensembl:ENSP00000435105.1
ensembl:ENSP00000435260.2
ensembl:ENSP00000435886.2
ensembl:ENSP00000493857.2
ensembl:ENSP00000494729.2
ensembl:ENSP00000502963.1
ensembl:ENSP00000503006.1
ensembl:ENSP00000503052.1
ensembl:ENSP00000503078.1
ensembl:ENSP00000503174.1
ensembl:ENSP00000503280.1
ensembl:ENSP00000503300.1
ensembl:ENSP00000503435.1
ensembl:ENSP00000503487.1
ensembl:ENSP00000503513.1
ensembl:ENSP00000503578.1
ensembl:ENSP00000503608.1
ensembl:ENSP00000503652.1
ensembl:ENSP00000503674.1
ensembl:ENSP00000503858.1
ensembl:ENSP00000503909.1
ensembl:ENSP00000504161.1
ensembl:ENSP00000504226.1
ensembl:ENSP00000504336.1
ensembl:ENSP00000504480.1
ensembl:ENSP00000504638.1
ensembl:ENSP00000504659.1
ensembl:ENSP00000504797.1
ensembl:ENSP00000518417.1
ensembl:ENSP00000518418.1
ensembl:ENSP00000518419.1
ensembl:ENSP00000518420.1
ensembl:ENSP00000518421.1
ensembl:ENSP00000518426.1
ensembl:ENSP00000518427.1
ensembl:ENSP00000518428.1
ensembl:ENSP00000518429.1
ensembl:ENSP00000518430.1
ensembl:ENSP00000518431.1
ensembl:ENSP00000518432.1
ensembl:ENSP00000518433.1
ensembl:ENSP00000518434.1
ensembl:ENSP00000518435.1
ensembl:ENSP00000518436.1
ensembl:ENSP00000518437.1
ensembl:ENSP00000518438.1
ensembl:ENSP00000518440.1
ensembl:ENSP00000518441.1
ensembl:ENSP00000518442.1
ensembl:ENSP00000518443.1
ensembl:ENSP00000518444.1
ensembl:ENSP00000518445.1
ensembl:ENSP00000518448.1
ensembl:ENSP00000518449.1
ensembl:ENSP00000518450.1
ensembl:ENSP00000518452.1
ensembl:ENSP00000518455.1
ensembl:ENSP00000518456.1
ensembl:ENSP00000518457.1
ensembl:ENSP00000518460.1
ensembl:ENSP00000518464.1
ensembl:ENSP00000518466.1
ensembl:ENSP00000518468.1
ensembl:ENSP00000518469.1
Alternative identifier for interactor Bintact:EBI-985303
uniprotkb:Q8N632
uniprotkb:Q9HD92
uniprotkb:Q9NY70
uniprotkb:Q9NYL3
uniprotkb:Q96GK1
ensembl:ENSP00000376285.2
ensembl:ENSP00000440970.1
ensembl:ENSP00000465726.2
Aliases for Apsi-mi:catb_human(display_long)
uniprotkb:Cathepsin B1(gene name synonym)
uniprotkb:APP secretase(gene name synonym)
uniprotkb:CTSB(gene name)
psi-mi:CTSB(display_short)
uniprotkb:CPSB(gene name synonym)
Aliases for Bpsi-mi:sphk1_human(display_long)
uniprotkb:Acetyltransferase SPHK1(gene name synonym)
uniprotkb:SK1(gene name synonym)
uniprotkb:SPHK(gene name synonym)
uniprotkb:SPHK1(gene name)
psi-mi:SPHK1(display_short)
uniprotkb:SPK(gene name synonym)
Interaction detection methodspsi-mi:"MI:0435"(protease assay)
First authorTaha et al. (2006)
Identifier of the publicationpubmed:17064696
imex:IM-11352
mint:MINT-5219264
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0194"(cleavage reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7057027
mint:MINT-3974318
imex:IM-11352-4
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AEnzyme
Biological role BEnzyme target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F4 F3
comment:homomint
comment:mint
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2006/12/18
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bmutation decreasing interaction:123-123(MINT-3974323)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BWestern blot