Curation Details
Interaction ID: MINT-3391445

Unique identifier for interactor Auniprotkb:O15519-1
Unique identifier for interactor Buniprotkb:P45985
Alternative identifier for interactor Aintact:EBI-4567563
ensembl:ENSP00000312455.2
ensembl:ENSP00000399420.2
intact:EBI-7093779
intact:MINT-2589696
intact:EBI-7093972
intact:EBI-7093921
intact:EBI-7093724
intact:EBI-7093827
intact:EBI-8019287
intact:EBI-7158298
intact:EBI-7093876
Alternative identifier for interactor Bintact:EBI-447868
uniprotkb:D3DTS5
uniprotkb:Q5U0B8
uniprotkb:B2R7N7
uniprotkb:B3KYB2
uniprotkb:Q6FHX4
uniprotkb:Q6P9H2
uniprotkb:Q6PIE6
ensembl:ENSP00000262445.5
intact:EBI-28973354
Aliases for Apsi-mi:o15519-1(display_long)
uniprotkb:FLIP-L(isoform synonym)
uniprotkb:CLARP1(isoform synonym)
uniprotkb:MRIT alpha-1(isoform synonym)
uniprotkb:CASH alpha(isoform synonym)
uniprotkb:I-FLICE 1(isoform synonym)
uniprotkb:FLAME-1 gamma(isoform synonym)
uniprotkb:Usurpin alpha(isoform synonym)
uniprotkb:CFLAR(gene name)
psi-mi:CFLAR(display_short)
uniprotkb:CASH(gene name synonym)
uniprotkb:CASP8AP1(gene name synonym)
uniprotkb:CLARP(gene name synonym)
uniprotkb:MRIT(gene name synonym)
uniprotkb:Caspase homolog(gene name synonym)
uniprotkb:Caspase-eight-related protein(gene name synonym)
uniprotkb:Caspase-like apoptosis regulatory protein(gene name synonym)
uniprotkb:Cellular FLICE-like inhibitory protein(gene name synonym)
uniprotkb:FADD-like antiapoptotic molecule 1(gene name synonym)
uniprotkb:Inhibitor of FLICE(gene name synonym)
uniprotkb:MACH-related inducer of toxicity(gene name synonym)
uniprotkb:Usurpin(gene name synonym)
Aliases for Bpsi-mi:mp2k4_human(display_long)
uniprotkb:JNK-activating kinase 1(gene name synonym)
uniprotkb:c-Jun N-terminal kinase kinase 1(gene name synonym)
uniprotkb:SAPK/ERK kinase 1(gene name synonym)
uniprotkb:MAP2K4(gene name)
psi-mi:MAP2K4(display_short)
uniprotkb:JNKK1(gene name synonym)
uniprotkb:MKK4(gene name synonym)
uniprotkb:PRKMK4(gene name synonym)
uniprotkb:SERK1(gene name synonym)
uniprotkb:MEK4(gene name synonym)
uniprotkb:MAPK/ERK kinase 4(gene name synonym)
uniprotkb:SKK1(gene name synonym)
uniprotkb:SEK1(gene name synonym)
uniprotkb:Stress-activated protein kinase kinase 1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorNakajima et al. (2006)
Identifier of the publicationpubmed:17110930
imex:IM-11199
mint:MINT-5219344
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7093807
mint:MINT-3391445
imex:IM-11199-2
Confidence scoreintact-miscore:0.40
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F5B
comment:Only if MEKK1 is also overexpressed.
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293)
taxid:9606(Homo sapiens HEK293 embryonic kidney cell)
Parameters of the interaction-
Creation date2006/11/30
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Aflag tag:?-?(MINT-3391452)
Feature(s) for interactor Bha tag:?-?(MINT-3391460)
Stoichiometry for interactor A-
Stoichiometry for interactor B1
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification