Curation Details
Interaction ID: MINT-3390536

Unique identifier for interactor Auniprotkb:Q15118
Unique identifier for interactor Buniprotkb:Q16513
Alternative identifier for interactor Aintact:EBI-7016221
uniprotkb:B7Z937
uniprotkb:E9PD65
uniprotkb:Q308M4
ensembl:ENSP00000282077.3
ensembl:ENSP00000386985.1
uniprotkb:B2R6T1
intact:MINT-2881420
uniprotkb:D3DPD8
Alternative identifier for interactor Bintact:EBI-2511350
ensembl:ENSP00000359552.3
uniprotkb:Q9H1W4
uniprotkb:D3DT24
uniprotkb:B4DQ21
uniprotkb:B4DTP5
uniprotkb:B4DVG1
uniprotkb:Q08AF4
Aliases for Apsi-mi:pdk1_human(display_long)
uniprotkb:PDK1(gene name)
psi-mi:PDK1(display_short)
uniprotkb:PDHK1(gene name synonym)
uniprotkb:Pyruvate dehydrogenase kinase isoform 1(gene name synonym)
Aliases for Bpsi-mi:pkn2_human(display_long)
uniprotkb:PKN2(gene name)
psi-mi:PKN2(display_short)
uniprotkb:PRK2(gene name synonym)
uniprotkb:PRKCL2(gene name synonym)
uniprotkb:Protein kinase C-like 2(gene name synonym)
uniprotkb:Protein-kinase C-related kinase 2(gene name synonym)
uniprotkb:PKN gamma(gene name synonym)
Interaction detection methodspsi-mi:"MI:0424"(protein kinase assay)
First authorEngel et al. (2006)
Identifier of the publicationpubmed:17110931
imex:IM-10909
mint:MINT-5219347
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0217"(phosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7094666
mint:MINT-3390536
imex:IM-10909-2
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AEnzyme
Biological role BEnzyme target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:T1
kinetics:IC50 3,7 micromolar
comment:homomint
comment:mint
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2006/11/30
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Amutation decreasing interaction:131-131(MINT-3390538)
Feature(s) for interactor Bbinding-associated region:961-984(MINT-3390546)
Stoichiometry for interactor A1
Stoichiometry for interactor B1
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BPeptide synthesis