| Unique identifier for interactor A | uniprotkb:O15350-1 |
| Unique identifier for interactor B | uniprotkb:Q96J02 |
| Alternative identifier for interactor A | intact:EBI-389619 intact:EBI-7470973 intact:EBI-7471076 intact:EBI-7471099 intact:EBI-7471381 intact:EBI-7807052 intact:EBI-7807687 intact:EBI-7164857 intact:EBI-7805920 intact:EBI-7164970 intact:EBI-7471237 intact:EBI-7807120 intact:EBI-7807786 intact:EBI-7805669 intact:EBI-8585153 intact:EBI-7807280 intact:EBI-7807483 intact:EBI-7805754 intact:EBI-7806017 intact:EBI-7470879 intact:EBI-7471009 intact:EBI-7806994 intact:MINT-97785 intact:EBI-7805839 intact:EBI-7088676 intact:EBI-7807086 intact:EBI-7807154 intact:EBI-7805964 ensembl:ENSP00000367545.4 ensembl:ENSP00000518863.1 ensembl:ENSP00000518864.1 |
| Alternative identifier for interactor B | intact:EBI-1564678 uniprotkb:O43584 uniprotkb:Q5TEL0 uniprotkb:Q96F66 uniprotkb:Q9BY75 uniprotkb:Q9H451 uniprotkb:Q9H4U5 uniprotkb:A6NEW4 uniprotkb:Q5QP37 uniprotkb:E1P5P3 uniprotkb:B4E234 uniprotkb:F5H217 ensembl:ENSP00000262650.5 ensembl:ENSP00000499786.1 |
| Aliases for A | psi-mi:o15350-1(display_long) uniprotkb:TP73(gene name) psi-mi:TP73(display_short) uniprotkb:P73(gene name synonym) uniprotkb:p53-like transcription factor(gene name synonym) uniprotkb:p53-related protein(gene name synonym) |
| Aliases for B | psi-mi:itch_human(display_long) uniprotkb:HECT-type E3 ubiquitin transferase Itchy homolog(gene name synonym) uniprotkb:Atrophin-1-interacting protein 4(gene name synonym) uniprotkb:NFE2-associated polypeptide 1(gene name synonym) uniprotkb:ITCH(gene name) psi-mi:ITCH(display_short) |
| Interaction detection methods | psi-mi:"MI:0096"(pull down) |
| First author | Rossi et al. (2005) |
| Identifier of the publication | pubmed:15678106 imex:IM-14129 mint:MINT-5217499 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0220"(ubiquitination reaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-7471020 mint:MINT-3389196 imex:IM-14129-2 |
| Confidence score | intact-miscore:0.64 |
| Complex expansion | - |
| Biological role A | Enzyme target |
| Biological role B | Enzyme |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | comment:"\"We used a recombinant Itch (GST‐Itch) (Qiu et al, 2000), in a reconstituted in vitro ubiquitination system containing Ub, wheat E1, human E2 (UbcH7), ATP, and in vitro synthesized radiolabelled [35S]TAp73α protein as substrate. In the presence of purified GST‐Itch, the TAp73α protein was ubiquitinated\"" figure legend:F2A comment:homomint comment:mint dataset:Virus - Publications including interactions involving viral proteins curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2006/11/25 |
| Update date | 2024/11/26 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | glutathione s tranferase tag:?-?(MINT-3389210) |
| Stoichiometry for interactor A | 1 |
| Stoichiometry for interactor B | 1 |
| Participant identification method for interactor A | Nucleotide sequence identification |
| Participant identification method for interactor B | Nucleotide sequence identification |