| Unique identifier for interactor A | uniprotkb:Q92547 | 
| Unique identifier for interactor B | uniprotkb:P03120 | 
| Alternative identifier for interactor A | intact:EBI-308302 uniprotkb:Q7LGC1 uniprotkb:Q9UEB9 ensembl:ENSP00000260810.5 uniprotkb:B7Z7W8  | 
| Alternative identifier for interactor B | intact:EBI-1779322 uniprotkb:Q71BI4  | 
| Aliases for A | psi-mi:topb1_human(display_long) uniprotkb:KIAA0259(gene name synonym) uniprotkb:TOPBP1(gene name) psi-mi:TOPBP1(display_short) uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym) uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym)  | 
| Aliases for B | psi-mi:ve2_hpv16(display_long) uniprotkb:E2(gene name) psi-mi:E2(display_short)  | 
| Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) | 
| First author | Liu et al. (2006) | 
| Identifier of the publication | pubmed:17006541 imex:IM-11117 mint:MINT-5219150  | 
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens)  | 
| NCBI Taxonomy identifier for interactor B | taxid:333760(hpv16) taxid:333760(Human papillomavirus type 16)  | 
| Interaction types | psi-mi:"MI:0915"(physical association) | 
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) | 
| Interaction identifier(s) in the corresponding source database | intact:EBI-6997838 mint:MINT-3379305 imex:IM-11117-12  | 
| Confidence score | intact-miscore:0.67 | 
| Complex expansion | - | 
| Biological role A | Unspecified role | 
| Biological role B | Unspecified role | 
| Experimental role A | Prey | 
| Experimental role B | Bait | 
| Interactor type A | Protein | 
| Interactor type B | Protein | 
| Annotations for the interaction | figure legend:F7A comment:homomint comment:mint dataset:Virus - Publications including interactions involving viral proteins curation depth:imex curation full coverage:Only protein-protein interactions  | 
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-293) taxid:9606(Homo sapiens HEK293 embryonic kidney cell)  | 
| Parameters of the interaction | - | 
| Creation date | 2006/11/02 | 
| Update date | 2025/08/11 | 
| negative Boolean value | false | 
| Feature(s) for interactor A | mutation decreasing interaction:1159-1159(MINT-3379330) | 
| Feature(s) for interactor B | green fluorescent protein tag:?-?(MINT-3379309) | 
| Stoichiometry for interactor A | 1 | 
| Stoichiometry for interactor B | 1 | 
| Participant identification method for interactor A | Western blot | 
| Participant identification method for interactor B | Nucleotide sequence identification |