Curation Details
Interaction ID: MINT-3379305

Unique identifier for interactor Auniprotkb:Q92547
Unique identifier for interactor Buniprotkb:P03120
Alternative identifier for interactor Aintact:EBI-308302
uniprotkb:B7Z7W8
ensembl:ENSP00000260810.5
uniprotkb:Q7LGC1
uniprotkb:Q9UEB9
Alternative identifier for interactor Bintact:EBI-1779322
uniprotkb:Q71BI4
Aliases for Apsi-mi:topb1_human(display_long)
uniprotkb:KIAA0259(gene name synonym)
uniprotkb:TOPBP1(gene name)
psi-mi:TOPBP1(display_short)
uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym)
uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym)
Aliases for Bpsi-mi:ve2_hpv16(display_long)
uniprotkb:E2(gene name)
psi-mi:E2(display_short)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorLiu et al. (2006)
Identifier of the publicationpubmed:17006541
imex:IM-11117
mint:MINT-5219150
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:333760(hpv16)
taxid:333760(Human papillomavirus type 16)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-6997838
mint:MINT-3379305
imex:IM-11117-12
Confidence scoreintact-miscore:0.67
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F7A
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293)
taxid:9606(Homo sapiens HEK293 embryonic kidney cell)
Parameters of the interaction-
Creation date2006/11/02
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Amutation decreasing interaction:1159-1159(MINT-3379330)
Feature(s) for interactor Bgreen fluorescent protein tag:?-?(MINT-3379309)
Stoichiometry for interactor A1
Stoichiometry for interactor B1
Participant identification method for interactor AWestern blot
Participant identification method for interactor BNucleotide sequence identification