| Unique identifier for interactor A | uniprotkb:Q92547 |
| Unique identifier for interactor B | uniprotkb:Q01094 |
| Alternative identifier for interactor A | intact:EBI-308302 uniprotkb:Q7LGC1 uniprotkb:Q9UEB9 uniprotkb:B7Z7W8 ensembl:ENSP00000260810.5 |
| Alternative identifier for interactor B | intact:EBI-448924 uniprotkb:Q13143 uniprotkb:Q92768 ensembl:ENSP00000345571.5 |
| Aliases for A | psi-mi:topb1_human(display_long) uniprotkb:KIAA0259(gene name synonym) uniprotkb:TOPBP1(gene name) psi-mi:TOPBP1(display_short) uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym) uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym) |
| Aliases for B | psi-mi:e2f1_human(display_long) uniprotkb:Retinoblastoma-associated protein 1(gene name synonym) uniprotkb:Retinoblastoma-binding protein 3(gene name synonym) uniprotkb:PBR3(gene name synonym) uniprotkb:E2F1(gene name) psi-mi:E2F1(display_short) uniprotkb:RBBP3(gene name synonym) uniprotkb:pRB-binding protein E2F-1(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0096"(pull down) |
| First author | Liu et al. (2006) |
| Identifier of the publication | pubmed:17006541 imex:IM-11117 mint:MINT-5219150 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-6997915 mint:MINT-3379112 imex:IM-11117-3 |
| Confidence score | intact-miscore:0.70 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Bait |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:F2D comment:phosphorylation of TopBP1 by Akt at Ser1159 is required for TopBP1 to bind E2F1. comment:homomint comment:mint dataset:Virus - Publications including interactions involving viral proteins curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2006/11/02 |
| Update date | 2025/03/31 |
| negative Boolean value | false |
| Feature(s) for interactor A | mutation disrupting interaction:1159-1159(MINT-3379127) |
| Feature(s) for interactor B | glutathione s tranferase tag:?-?(MINT-3379137) |
| Stoichiometry for interactor A | 1 |
| Stoichiometry for interactor B | 1 |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Nucleotide sequence identification |