Curation Details
Interaction ID: MINT-3379015

Unique identifier for interactor Auniprotkb:P31749
Unique identifier for interactor Buniprotkb:Q92547
Alternative identifier for interactor Aintact:EBI-296087
uniprotkb:Q9BWB6
uniprotkb:B2RAM5
ensembl:ENSP00000270202.4
ensembl:ENSP00000384293.2
ensembl:ENSP00000385326.2
ensembl:ENSP00000450688.1
ensembl:ENSP00000451166.1
ensembl:ENSP00000451828.1
ensembl:ENSP00000497822.1
ensembl:ENSP00000507879.1
uniprotkb:B7Z5R1
Alternative identifier for interactor Bintact:EBI-308302
uniprotkb:Q7LGC1
uniprotkb:Q9UEB9
uniprotkb:B7Z7W8
ensembl:ENSP00000260810.5
Aliases for Apsi-mi:akt1_human(display_long)
uniprotkb:AKT1(gene name)
psi-mi:AKT1(display_short)
uniprotkb:PKB(gene name synonym)
uniprotkb:RAC(gene name synonym)
uniprotkb:RAC-PK-alpha(gene name synonym)
uniprotkb:Protein kinase B(gene name synonym)
uniprotkb:Proto-oncogene c-Akt(gene name synonym)
uniprotkb:Protein kinase B alpha(gene name synonym)
Aliases for Bpsi-mi:topb1_human(display_long)
uniprotkb:KIAA0259(gene name synonym)
uniprotkb:TOPBP1(gene name)
psi-mi:TOPBP1(display_short)
uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym)
uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0424"(protein kinase assay)
First authorLiu et al. (2006)
Identifier of the publicationpubmed:17006541
imex:IM-11117
mint:MINT-5219150
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0217"(phosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-6997506
mint:MINT-3379015
imex:IM-11117-2
Confidence scoreintact-miscore:0.54
Complex expansion-
Biological role AEnzyme
Biological role BEnzyme target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F1B
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2006/11/02
Update date2024/09/11
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bmutation disrupting interaction:1159-1159(MINT-3379027)
glutathione s tranferase tag:?-?(MINT-3379021)
Stoichiometry for interactor A1
Stoichiometry for interactor B1
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification