Curation Details
Interaction ID: MINT-3378519

Unique identifier for interactor Auniprotkb:Q99814
Unique identifier for interactor Buniprotkb:Q15118
Alternative identifier for interactor Aintact:EBI-447470
uniprotkb:Q86VA2
uniprotkb:Q99630
ensembl:ENSP00000263734.3
Alternative identifier for interactor Bintact:EBI-7016221
uniprotkb:B7Z937
uniprotkb:E9PD65
uniprotkb:Q308M4
ensembl:ENSP00000282077.3
ensembl:ENSP00000386985.1
uniprotkb:B2R6T1
intact:MINT-2881420
uniprotkb:D3DPD8
Aliases for Apsi-mi:epas1_human(display_long)
uniprotkb:EPAS1(gene name)
psi-mi:EPAS1(display_short)
uniprotkb:HIF2A(gene name synonym)
uniprotkb:MOP2(gene name synonym)
uniprotkb:Member of PAS protein 2(gene name synonym)
uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)
uniprotkb:BHLHE73(gene name synonym)
uniprotkb:PASD2(gene name synonym)
uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)
uniprotkb:HIF-1-alpha-like factor(gene name synonym)
uniprotkb:PAS domain-containing protein 2(gene name synonym)
uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym)
Aliases for Bpsi-mi:pdk1_human(display_long)
uniprotkb:PDK1(gene name)
psi-mi:PDK1(display_short)
uniprotkb:PDHK1(gene name synonym)
uniprotkb:Pyruvate dehydrogenase kinase isoform 1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0424"(protein kinase assay)
First authorTo et al. (2006)
Identifier of the publicationpubmed:17024177
imex:IM-11383
mint:MINT-5219187
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0217"(phosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7016254
mint:MINT-3378519
imex:IM-11383-1
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AEnzyme target
Biological role BEnzyme
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F6E
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2006/11/02
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Amutation disrupting interaction:324-324(MINT-3378532)
binding-associated region:314-331(MINT-3378540)
Feature(s) for interactor B-
Stoichiometry for interactor A1
Stoichiometry for interactor B1
Participant identification method for interactor APeptide synthesis
Participant identification method for interactor BNucleotide sequence identification