Curation Details
Interaction ID: MINT-3371368

Unique identifier for interactor Auniprotkb:Q9Z200
Unique identifier for interactor Buniprotkb:P06213
Alternative identifier for interactor Aintact:EBI-8562298
intact:MINT-3371223
ensembl:ENSRNOP00000001935.5
ensembl:ENSRNOP00055000334
ensembl:ENSRNOP00060015809
Alternative identifier for interactor Bintact:EBI-475899
uniprotkb:Q17RW0
uniprotkb:Q59H98
uniprotkb:Q9UCB7
uniprotkb:Q9UCB8
uniprotkb:Q9UCB9
ensembl:ENSP00000303830.4
Aliases for Apsi-mi:sh2b2_rat(display_long)
uniprotkb:Aps(gene name synonym)
uniprotkb:Sh2b2(gene name)
psi-mi:Sh2b2(display_short)
uniprotkb:SH2 and PH domain-containing adapter protein APS(gene name synonym)
uniprotkb:Adapter protein with pleckstrin homology and Src homology 2 domains(gene name synonym)
Aliases for Bpsi-mi:insr_human(display_long)
uniprotkb:INSR(gene name)
psi-mi:INSR(display_short)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorHu et al. (2006)
Identifier of the publicationmint:MINT-5218799
pubmed:16824542
NCBI Taxonomy identifier for interactor Ataxid:10116(rat)
taxid:10116("Rattus norvegicus (Rat)")
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8562391
mint:MINT-3371368
Confidence scoreintact-miscore:0.40
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F5C
figure legend:F5A
comment:Cells were stimulated with Insulin
comment:homomint
comment:domino
comment:mint
NCBI Taxonomy identifier for the host organismtaxid:10029(crigr-cho)
taxid:10029(chinese hamster ovary cell line)
Parameters of the interaction-
Creation date2006/10/06
Update date2024/09/11
negative Boolean valuefalse
Feature(s) for interactor Amutation disrupting interaction:460-460(MINT-3371395)
mutation decreasing interaction:442-442(MINT-3371392)
binding-associated region:405-511(MINT-3371389)
mutation decreasing interaction:475-475(MINT-3371399)
flag tag:?-?(MINT-3371382)
Feature(s) for interactor B-
Stoichiometry for interactor A1
Stoichiometry for interactor B1
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BMonoclonal antibody western blot