Curation Details
Interaction ID: MINT-3089462

Unique identifier for interactor Auniprotkb:O15111
Unique identifier for interactor Buniprotkb:Q9Y6K9
Alternative identifier for interactor Aintact:EBI-81249
uniprotkb:O14666
uniprotkb:Q13132
uniprotkb:Q5W0I4
uniprotkb:Q92467
intact:EBI-28970970
ensembl:ENSP00000359424.6
Alternative identifier for interactor Bintact:EBI-81279
intact:EBI-356130
uniprotkb:Q7LBY6
uniprotkb:Q7Z7F1
ensembl:ENSP00000390368.3
ensembl:ENSP00000394934.2
ensembl:ENSP00000395205.2
ensembl:ENSP00000471166.1
ensembl:ENSP00000479662.1
Aliases for Apsi-mi:ikka_human(display_long)
uniprotkb:CHUK(gene name)
psi-mi:CHUK(display_short)
uniprotkb:IKKA(gene name synonym)
uniprotkb:TCF16(gene name synonym)
uniprotkb:I-kappa-B kinase 1(gene name synonym)
uniprotkb:Conserved helix-loop-helix ubiquitous kinase(gene name synonym)
uniprotkb:Nuclear factor NF-kappa-B inhibitor kinase alpha(gene name synonym)
uniprotkb:Transcription factor 16(gene name synonym)
Aliases for Bpsi-mi:nemo_human(display_long)
uniprotkb:IKBKG(gene name)
psi-mi:IKBKG(display_short)
uniprotkb:FIP3(gene name synonym)
uniprotkb:NEMO(gene name synonym)
uniprotkb:NF-kappa-B essential modifier(gene name synonym)
uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)
uniprotkb:IkB kinase-associated protein 1(gene name synonym)
uniprotkb:FIP-3(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorHermann et al. (2006)
Identifier of the publicationpubmed:16938294
imex:IM-10981
mint:MINT-5219009
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-6939297
mint:MINT-3089462
imex:IM-10981-1
Confidence scoreintact-miscore:0.97
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F3B
comment:Interaction occurs in T. annullata transformed cells. Anti-IKK antibody recognizes both IKK1 and IKK2
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-jurkat)
taxid:9606(Homo sapiens Jurkat T-cell leukemia cell)
Parameters of the interaction-
Creation date2006/09/22
Update date2024/11/06
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A1
Stoichiometry for interactor B1
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot