Curation Details
Interaction ID: MINT-2836265

Unique identifier for interactor Auniprotkb:P04731
Unique identifier for interactor Buniprotkb:P49407
Alternative identifier for interactor Aintact:EBI-8045030
ensembl:ENSP00000290705.8
uniprotkb:Q86YX5
intact:MINT-1781424
Alternative identifier for interactor Bintact:EBI-743313
intact:EBI-2561130
uniprotkb:B6V9G8
ensembl:ENSP00000409581.2
uniprotkb:O75625
uniprotkb:O75630
uniprotkb:Q2PP20
uniprotkb:Q9BTK8
Aliases for Apsi-mi:mt1a_human(display_long)
uniprotkb:MT1A(gene name)
psi-mi:MT1A(display_short)
uniprotkb:MT1S(gene name synonym)
uniprotkb:Metallothionein-IA(gene name synonym)
Aliases for Bpsi-mi:arrb1_human(display_long)
uniprotkb:Arrestin beta-1(gene name synonym)
uniprotkb:ARRB1(gene name)
psi-mi:ARRB1(display_short)
uniprotkb:ARR1(gene name synonym)
uniprotkb:Non-visual arrestin-2(gene name synonym)
Interaction detection methodspsi-mi:"MI:0012"(bioluminescence resonance energy transfer)
First authorLevoye et al. (2006)
Identifier of the publicationmint:MINT-5218751
pubmed:16778767
imex:IM-11102
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:2364"(proximity)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8551140
mint:MINT-2836265
imex:IM-11102-4
Confidence scoreintact-miscore:0.27
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role AFluorescence donor
Experimental role BFluorescence acceptor
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F9B
figure legend:F9C
comment:Dynamic recruitment of beta-arrestin 1 to MT1 was observed upon melatonin stimulation. Coexpression of Flag-GPR50 decreased the melatonin-induced BRET signal
comment:homomint
comment:mint
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293)
taxid:9606(Homo sapiens HEK293 embryonic kidney cell)
Parameters of the interaction-
Creation date2006/07/26
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Atag:?-?(MINT-2836269)
Feature(s) for interactor Byellow fluorescent protein tag:?-?(MINT-2836277)
Stoichiometry for interactor A1
Stoichiometry for interactor B1
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification