Curation Details
Interaction ID: MINT-2793613

Unique identifier for interactor Auniprotkb:P23588
Unique identifier for interactor Buniprotkb:Q14152
Alternative identifier for interactor Aintact:EBI-970310
uniprotkb:Q4G0E3
uniprotkb:Q53HQ2
uniprotkb:Q6GPH5
uniprotkb:Q6IB46
uniprotkb:Q8WYK5
uniprotkb:B4DS13
ensembl:ENSP00000262056.9
Alternative identifier for interactor Bintact:EBI-366617
uniprotkb:O00653
uniprotkb:Q15778
uniprotkb:B1AMV5
intact:EBI-28978176
uniprotkb:B4DYS1
uniprotkb:F5H335
ensembl:ENSP00000358140.3
Aliases for Apsi-mi:if4b_human(display_long)
uniprotkb:EIF4B(gene name)
psi-mi:EIF4B(display_short)
Aliases for Bpsi-mi:eif3a_human(display_long)
uniprotkb:EIF3A(gene name)
psi-mi:EIF3A(display_short)
uniprotkb:KIAA0139(gene name synonym)
uniprotkb:EIF3S10(gene name synonym)
uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym)
uniprotkb:eIF-3-theta(gene name synonym)
uniprotkb:eIF3 p167(gene name synonym)
uniprotkb:eIF3 p180(gene name synonym)
uniprotkb:eIF3 p185(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorShahbazian et al. (2006)
Identifier of the publicationpubmed:16763566
imex:IM-13959
mint:MINT-5218723
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8545244
mint:MINT-2793613
imex:IM-13959-2
Confidence scoreintact-miscore:0.67
Complex expansion-
Biological role AUnspecified role
Biological role BEnzyme
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F6B
figure legend:F6A
comment:Serum stimulation strongly enhanced the interaction between eIF4B and eIF3 in cells expressing wt and constitutively active RSK variants, but not in cells expressing the kinase-dead RSK.
comment:homomint
comment:mint
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hela)
taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)
Parameters of the interaction-
Creation date2006/07/14
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Amutation decreasing interaction:422-422(MINT-2793667)
flag tag:?-?(MINT-2793635)
mutation disrupting interaction:422-422(MINT-2793664)
Feature(s) for interactor B-
Stoichiometry for interactor A1
Stoichiometry for interactor B1
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BWestern blot