Curation Details
Interaction ID: MINT-1954012

Unique identifier for interactor Auniprotkb:P62991
Unique identifier for interactor Buniprotkb:O15105
Alternative identifier for interactor Aintact:EBI-413074
dip:DIP-29742N
uniprotkb:P02248
uniprotkb:P02249
uniprotkb:P02250
uniprotkb:Q29120
uniprotkb:Q62317
uniprotkb:Q64223
uniprotkb:Q8VCH1
uniprotkb:Q91887
uniprotkb:Q91888
uniprotkb:Q9CXY4
uniprotkb:Q9CZM0
uniprotkb:Q9D1R5
uniprotkb:Q9D8D9
uniprotkb:Q9ET23
uniprotkb:Q9ET24
uniprotkb:Q9Z0H9
Alternative identifier for interactor Bintact:EBI-3861591
uniprotkb:B7Z773
uniprotkb:O14740
uniprotkb:Q6DK23
uniprotkb:K7EQ10
ensembl:ENSP00000262158.2
Aliases for Apsi-mi:ubiq_mouse(display_long)
uniprotkb:Rps27a(gene name)
psi-mi:Rps27a(display_short)
uniprotkb:Uba80(gene name synonym)
uniprotkb:Ubcep1(gene name synonym)
uniprotkb:Uba52(gene name)
psi-mi:Uba52(display_short)
uniprotkb:Ubcep2(gene name synonym)
uniprotkb:Ubb(gene name)
psi-mi:Ubb(display_short)
uniprotkb:Ubc(gene name)
psi-mi:Ubc(display_short)
Aliases for Bpsi-mi:smad7_human(display_long)
uniprotkb:SMAD7(gene name)
psi-mi:SMAD7(display_short)
uniprotkb:MADH7(gene name synonym)
uniprotkb:MADH8(gene name synonym)
uniprotkb:Mothers against decapentaplegic homolog 8(gene name synonym)
uniprotkb:SMAD family member 7(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorLiu et al. (2006)
Identifier of the publicationpubmed:16601693
imex:IM-11115
mint:MINT-5218493
NCBI Taxonomy identifier for interactor Ataxid:10090(mouse)
taxid:10090(Mus musculus)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0220"(ubiquitination reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8302540
mint:MINT-1954012
imex:IM-11115-30
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F6
comment:The over-expression of arkadia and axin increase the ubiquitination of smad7.
comment:mint
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293t)
taxid:9606(Homo sapiens HEK293T embryonic kidney cell)
Parameters of the interaction-
Creation date2006/05/11
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Amyc tag:?-?(MINT-1954018)
Feature(s) for interactor Bflag tag:?-?(MINT-1954030)
Stoichiometry for interactor A1
Stoichiometry for interactor B1
Participant identification method for interactor AWestern blot
Participant identification method for interactor BNucleotide sequence identification