Curation Details
Interaction ID: MINT-19267

Unique identifier for interactor Auniprotkb:P62994
Unique identifier for interactor Buniprotkb:Q14118
Alternative identifier for interactor Aintact:EBI-401775
ensembl:ENSRNOP00055047104
ensembl:ENSRNOP00060027341
ensembl:ENSRNOP00065028065
uniprotkb:P29354
uniprotkb:Q14450
uniprotkb:Q5BKA7
uniprotkb:Q63057
uniprotkb:Q63059
Alternative identifier for interactor Bintact:EBI-1755945
uniprotkb:A8K6M7
uniprotkb:Q969J9
ensembl:ENSP00000312435.2
ensembl:ENSP00000387859.2
ensembl:ENSP00000388833.2
ensembl:ENSP00000401382.3
ensembl:ENSP00000401805.2
ensembl:ENSP00000405859.2
ensembl:ENSP00000410145.3
ensembl:ENSP00000412067.2
ensembl:ENSP00000415321.4
ensembl:ENSP00000501140.1
ensembl:ENSP00000501165.2
ensembl:ENSP00000513216.1
ensembl:ENSP00000513217.1
ensembl:ENSP00000513218.1
Aliases for Apsi-mi:grb2_rat(display_long)
uniprotkb:Grb2(gene name)
psi-mi:Grb2(display_short)
uniprotkb:Ash(gene name synonym)
uniprotkb:Adapter protein GRB2(gene name synonym)
uniprotkb:SH2/SH3 adapter GRB2(gene name synonym)
uniprotkb:Protein Ash(gene name synonym)
Aliases for Bpsi-mi:dag1_human(display_long)
uniprotkb:DAG1(gene name)
psi-mi:DAG1(display_short)
uniprotkb:Dystrophin-associated glycoprotein 1(gene name synonym)
uniprotkb:Dystroglycan(gene name synonym)
Interaction detection methodspsi-mi:"MI:0411"(enzyme linked immunosorbent assay)
First authorRusso et al. (2000)
Identifier of the publicationpubmed:10903901
mint:MINT-5212801
NCBI Taxonomy identifier for interactor Ataxid:10116(rat)
taxid:10116("Rattus norvegicus (Rat)")
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7351553
mint:MINT-19267
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:Both the SH3 domains of Grb2 binds the destroglycan, but the N-terminal binds more strongly.
comment:homomint
comment:mint
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2001/03/30
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:1-57(MINT-428025)
Feature(s) for interactor Bbinding-associated region:821-895(MINT-428031)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant