| Unique identifier for interactor A | uniprotkb:Q07889 |
| Unique identifier for interactor B | uniprotkb:P62994 |
| Alternative identifier for interactor A | intact:EBI-297487 intact:EBI-28968641 uniprotkb:A8K2G3 uniprotkb:B4DXG2 ensembl:ENSP00000384675.2 |
| Alternative identifier for interactor B | intact:EBI-401775 uniprotkb:P29354 uniprotkb:Q14450 uniprotkb:Q5BKA7 uniprotkb:Q63057 uniprotkb:Q63059 |
| Aliases for A | psi-mi:sos1_human(display_long) uniprotkb:SOS1(gene name) psi-mi:SOS1(display_short) |
| Aliases for B | psi-mi:grb2_rat(display_long) uniprotkb:Grb2(gene name) psi-mi:Grb2(display_short) uniprotkb:Ash(gene name synonym) uniprotkb:Adapter protein GRB2(gene name synonym) uniprotkb:SH2/SH3 adapter GRB2(gene name synonym) uniprotkb:Protein Ash(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0019"(coimmunoprecipitation) |
| First author | Li et al. (2001) |
| Identifier of the publication | pubmed:11726515 mint:MINT-5214841 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:10116(rat) taxid:10116("Rattus norvegicus (Rat)") |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-8047271 mint:MINT-19145 |
| Confidence score | intact-miscore:0.40 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Bait |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | comment:Tyr209 phosphorilation by EGF receptor and binding to BCR/ABL inhibits Grb-2 association with SOs-1 protein comment:mint partial coverage:partial coverage curation depth:rapid curation |
| NCBI Taxonomy identifier for the host organism | taxid:-4(in vivo) taxid:-4(in vivo) |
| Parameters of the interaction | - |
| Creation date | 2002/02/22 |
| Update date | 2025/08/11 |
| negative Boolean value | false |
| Feature(s) for interactor A | binding-associated region:?-?(MINT-595383) |
| Feature(s) for interactor B | binding-associated region:?-?(MINT-595378) |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Predetermined participant |