Curation Details
Interaction ID: MINT-1894217

Unique identifier for interactor Auniprotkb:P06213
Unique identifier for interactor Buniprotkb:P35568
Alternative identifier for interactor Aintact:EBI-475899
uniprotkb:Q17RW0
uniprotkb:Q59H98
uniprotkb:Q9UCB7
uniprotkb:Q9UCB8
uniprotkb:Q9UCB9
ensembl:ENSP00000303830.4
Alternative identifier for interactor Bintact:EBI-517592
ensembl:ENSP00000304895.4
intact:EBI-28983786
Aliases for Apsi-mi:insr_human(display_long)
uniprotkb:INSR(gene name)
psi-mi:INSR(display_short)
Aliases for Bpsi-mi:irs1_human(display_long)
uniprotkb:IRS1(gene name)
psi-mi:IRS1(display_short)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorNouaille et al. (2006)
Identifier of the publicationpubmed:16582879
imex:IM-11220
mint:MINT-5218466
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8289050
mint:MINT-1894217
imex:IM-11220-4
Confidence scoreintact-miscore:0.70
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F4A
comment:Interaction is insulin dependent. Overexpression of Grb14 decreases interaction
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293)
taxid:9606(Homo sapiens HEK293 embryonic kidney cell)
Parameters of the interaction-
Creation date2006/05/03
Update date2024/09/11
negative Boolean valuefalse
Feature(s) for interactor Ayellow fluorescent protein tag:?-?(MINT-1894238)
Feature(s) for interactor B-
Stoichiometry for interactor A1
Stoichiometry for interactor B1
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BWestern blot