Curation Details
Interaction ID: MINT-1894168

Unique identifier for interactor Auniprotkb:P18031
Unique identifier for interactor Buniprotkb:P06213
Alternative identifier for interactor Aintact:EBI-968788
uniprotkb:Q5TGD8
uniprotkb:Q9BQV9
uniprotkb:Q9NQQ4
ensembl:ENSP00000360683.3
Alternative identifier for interactor Bintact:EBI-475899
uniprotkb:Q17RW0
uniprotkb:Q59H98
uniprotkb:Q9UCB7
uniprotkb:Q9UCB8
uniprotkb:Q9UCB9
ensembl:ENSP00000303830.4
Aliases for Apsi-mi:ptn1_human(display_long)
uniprotkb:PTPN1(gene name)
psi-mi:PTPN1(display_short)
uniprotkb:PTP1B(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)
Aliases for Bpsi-mi:insr_human(display_long)
uniprotkb:INSR(gene name)
psi-mi:INSR(display_short)
Interaction detection methodspsi-mi:"MI:0012"(bioluminescence resonance energy transfer)
First authorNouaille et al. (2006)
Identifier of the publicationpubmed:16582879
imex:IM-11220
mint:MINT-5218466
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:2364"(proximity)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8288896
mint:MINT-1894168
imex:IM-11220-2
Confidence scoreintact-miscore:0.98
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role AFluorescence acceptor
Experimental role BFluorescence donor
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F2A
comment:Interaction is insulin dependent. Overexpression of Grb14 decreases interaction
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293)
taxid:9606(Homo sapiens HEK293 embryonic kidney cell)
Parameters of the interaction-
Creation date2006/05/03
Update date2024/09/11
negative Boolean valuefalse
Feature(s) for interactor Ayellow fluorescent protein tag:?-?(MINT-1894175)
mutation increasing interaction:181-181(MINT-1894189)
Feature(s) for interactor Bfusion protein:?-?(MINT-1894183)
Stoichiometry for interactor A1
Stoichiometry for interactor B1
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification