Curation Details
Interaction ID: MINT-1893011

Unique identifier for interactor Auniprotkb:Q13480
Unique identifier for interactor Buniprotkb:P27986
Alternative identifier for interactor Aintact:EBI-517684
uniprotkb:Q4W5G2
uniprotkb:Q6P1W2
ensembl:ENSP00000262994.4
uniprotkb:A8K152
Alternative identifier for interactor Bintact:EBI-79464
intact:EBI-28974553
uniprotkb:Q15747
uniprotkb:Q4VBZ7
uniprotkb:Q53EM6
uniprotkb:Q8IXA2
uniprotkb:Q8N1C5
uniprotkb:D3DWA0
uniprotkb:B3KT19
uniprotkb:E7EX19
ensembl:ENSP00000428056.1
ensembl:ENSP00000429277.1
ensembl:ENSP00000513316.1
ensembl:ENSP00000513333.1
Aliases for Apsi-mi:gab1_human(display_long)
uniprotkb:Growth factor receptor bound protein 2-associated protein 1(gene name synonym)
uniprotkb:GRB2-associated binder 1(gene name synonym)
uniprotkb:GAB1(gene name)
psi-mi:GAB1(display_short)
Aliases for Bpsi-mi:p85a_human(display_long)
uniprotkb:PIK3R1(gene name)
psi-mi:PIK3R1(display_short)
uniprotkb:GRB1(gene name synonym)
uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorHanna et al. (2006)
Identifier of the publicationpubmed:16638574
imex:IM-10968
mint:MINT-5218554
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8494687
mint:MINT-1893011
imex:IM-10968-1
Confidence scoreintact-miscore:0.80
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F4
comment:The interaction occurs in presence of EGF. Gab1 amount precipitated with GST-p85 appears inversely proportional to SHP-2 catalytic activity.
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2006/04/28
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Amyc tag:?-?(MINT-1893025)
Feature(s) for interactor Bglutathione s tranferase tag:?-?(MINT-1893018)
Stoichiometry for interactor A1
Stoichiometry for interactor B1
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification