Curation Details
Interaction ID: MINT-18637

Unique identifier for interactor Auniprotkb:P46940
Unique identifier for interactor Buniprotkb:P60953
Alternative identifier for interactor Aintact:EBI-297509
intact:EBI-25601492
uniprotkb:A7MBM3
ensembl:ENSP00000268182.5
Alternative identifier for interactor Bintact:EBI-81752
uniprotkb:P21181
uniprotkb:P25763
uniprotkb:Q7L8R5
uniprotkb:Q9UDI2
ensembl:ENSP00000341072.3
ensembl:ENSP00000383118.1
ensembl:ENSP00000398327.2
ensembl:ENSP00000499457.1
ensembl:ENSP00000499612.1
ensembl:ENSP00000512176.1
ensembl:ENSP00000512177.1
ensembl:ENSP00000512178.1
ensembl:ENSP00000512179.1
ensembl:ENSP00000512180.1
ensembl:ENSP00000512182.1
Aliases for Apsi-mi:iqga1_human(display_long)
uniprotkb:IQGAP1(gene name)
psi-mi:IQGAP1(display_short)
uniprotkb:KIAA0051(gene name synonym)
uniprotkb:p195(gene name synonym)
Aliases for Bpsi-mi:cdc42_human(display_long)
uniprotkb:CDC42(gene name)
psi-mi:CDC42(display_short)
uniprotkb:G25K GTP-binding protein(gene name synonym)
Interaction detection methodspsi-mi:"MI:0428"(imaging technique)
First authorHart et al. (1996)
Identifier of the publicationmint:MINT-5221088
pubmed:8670801
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8683630
mint:MINT-18637
Confidence scoreintact-miscore:0.96
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:IQGAP1 bound to and inhibited the GTPase activity of cdc42Hs.
comment:homomint
comment:mint
NCBI Taxonomy identifier for the host organismtaxid:-4(in vivo)
taxid:-4(in vivo)
Parameters of the interaction-
Creation date2001/12/30
Update date2024/11/12
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:?-?(MINT-1518307)
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant