| Unique identifier for interactor A | uniprotkb:P32577 |
| Unique identifier for interactor B | uniprotkb:P29352 |
| Alternative identifier for interactor A | intact:EBI-7482976 intact:MINT-1535121 uniprotkb:Q4G003 ensembl:ENSRNOP00000026358.5 |
| Alternative identifier for interactor B | intact:EBI-8654263 ensembl:ENSMUSP00000029433.8 uniprotkb:Q7TMP9 intact:MINT-1535132 |
| Aliases for A | psi-mi:csk_rat(display_long) uniprotkb:Csk(gene name) psi-mi:Csk(display_short) uniprotkb:C-Src kinase(gene name synonym) |
| Aliases for B | psi-mi:ptn22_mouse(display_long) uniprotkb:Ptpn22(gene name) psi-mi:Ptpn22(display_short) uniprotkb:Ptpn8(gene name synonym) uniprotkb:Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP(gene name synonym) uniprotkb:PEST-domain phosphatase(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0096"(pull down) |
| First author | Gregorieff et al. (1998) |
| Identifier of the publication | pubmed:9582365 mint:MINT-6547857 |
| NCBI Taxonomy identifier for interactor A | taxid:10116(rat) taxid:10116("Rattus norvegicus (Rat)") |
| NCBI Taxonomy identifier for interactor B | taxid:10090(mouse) taxid:10090(Mus musculus) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-8688494 mint:MINT-18529 |
| Confidence score | intact-miscore:0.44 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | comment:"\"The alanine scanning reveals the importance of the following residues in the sequence 613PPPLPERTPESFIV626: P614;L616;P617;R619, in the proline rich core of class 2, and T620;I625;V626 in the carboxy-terminal part. Mutation of these residues reduce binding by 10- and 5-fold in vitro.The L616;P617 are not required in vivo. Approximatively 25-50% of PEP is bound to Csk in hematopoietic cells.\"" comment:homomint comment:mint partial coverage:partial coverage |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2001/09/26 |
| Update date | 2026/01/11 |
| negative Boolean value | false |
| Feature(s) for interactor A | binding-associated region:13-96(MINT-1535145) |
| Feature(s) for interactor B | binding-associated region:605-629(MINT-1535151) |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Predetermined participant |