Curation Details
Interaction ID: MINT-1777462

Unique identifier for interactor Auniprotkb:P06400
Unique identifier for interactor Buniprotkb:Q01094
Alternative identifier for interactor Aintact:EBI-491274
uniprotkb:P78499
uniprotkb:Q5VW46
uniprotkb:Q8IZL4
uniprotkb:A8K5E3
ensembl:ENSP00000267163.4
Alternative identifier for interactor Bintact:EBI-448924
ensembl:ENSP00000345571.5
uniprotkb:Q13143
uniprotkb:Q92768
Aliases for Apsi-mi:rb_human(display_long)
uniprotkb:pRb(gene name synonym)
uniprotkb:pp110(gene name synonym)
uniprotkb:p105-Rb(gene name synonym)
uniprotkb:RB1(gene name)
psi-mi:RB1(display_short)
uniprotkb:p110-RB1(gene name synonym)
Aliases for Bpsi-mi:e2f1_human(display_long)
uniprotkb:Retinoblastoma-associated protein 1(gene name synonym)
uniprotkb:Retinoblastoma-binding protein 3(gene name synonym)
uniprotkb:PBR3(gene name synonym)
uniprotkb:E2F1(gene name)
psi-mi:E2F1(display_short)
uniprotkb:RBBP3(gene name synonym)
uniprotkb:pRB-binding protein E2F-1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorMarkham et al. (2006)
Identifier of the publicationpubmed:16374512
imex:IM-11154
mint:MINT-5218170
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7978810
mint:MINT-1777462
imex:IM-11154-3
Confidence scoreintact-miscore:0.97
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F3C
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293)
taxid:9606(Homo sapiens HEK293 embryonic kidney cell)
Parameters of the interaction-
Creation date2006/03/07
Update date2024/09/11
negative Boolean valuefalse
Feature(s) for interactor Aha tag:n-n(MINT-1777468)
mutation decreasing interaction:873-873(MINT-1777478)
binding-associated region:763-928(MINT-1777474)
mutation decreasing interaction:874-874(MINT-1777476)
Feature(s) for interactor B-
Stoichiometry for interactor A1
Stoichiometry for interactor B1
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BWestern blot