| Unique identifier for interactor A | uniprotkb:P31749 |
| Unique identifier for interactor B | uniprotkb:P46527 |
| Alternative identifier for interactor A | intact:EBI-296087 uniprotkb:Q9BWB6 uniprotkb:B2RAM5 ensembl:ENSP00000270202.4 ensembl:ENSP00000384293.2 ensembl:ENSP00000385326.2 ensembl:ENSP00000450688.1 ensembl:ENSP00000451166.1 ensembl:ENSP00000451828.1 ensembl:ENSP00000497822.1 ensembl:ENSP00000507879.1 uniprotkb:B7Z5R1 |
| Alternative identifier for interactor B | intact:EBI-519280 uniprotkb:Q16307 uniprotkb:Q9BUS6 ensembl:ENSP00000228872.4 ensembl:ENSP00000507272.1 uniprotkb:Q5U0H2 |
| Aliases for A | psi-mi:akt1_human(display_long) uniprotkb:AKT1(gene name) psi-mi:AKT1(display_short) uniprotkb:PKB(gene name synonym) uniprotkb:RAC(gene name synonym) uniprotkb:RAC-PK-alpha(gene name synonym) uniprotkb:Protein kinase B(gene name synonym) uniprotkb:Proto-oncogene c-Akt(gene name synonym) uniprotkb:Protein kinase B alpha(gene name synonym) |
| Aliases for B | psi-mi:cdn1b_human(display_long) uniprotkb:Cyclin-dependent kinase inhibitor p27(gene name synonym) uniprotkb:p27Kip1(gene name synonym) uniprotkb:CDKN1B(gene name) psi-mi:CDKN1B(display_short) uniprotkb:KIP1(gene name synonym) uniprotkb:p27(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0019"(coimmunoprecipitation) |
| First author | Fujita et al. (2002) |
| Identifier of the publication | pubmed:12042314 mint:MINT-5215444 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0217"(phosphorylation reaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-8447946 mint:MINT-17679 |
| Confidence score | intact-miscore:0.63 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | comment:"\"- coIP with Flag-p27 and anti Akt ( both proteins over-expressed level)rn- Akt activated phosphorylates p27 : in vivo overexpression both proteins and Akt mutants ( inactive)rn- T198 is phosphorylated by Akt:- 293 transfected with Flag-p27 and Akt ( active or inactive) with different mutants of p27 . Only T198A is not phosphorylated by Akt rn\"" comment:homomint comment:mint dataset:Virus - Publications including interactions involving viral proteins partial coverage:partial coverage |
| NCBI Taxonomy identifier for the host organism | taxid:-4(in vivo) taxid:-4(in vivo) |
| Parameters of the interaction | - |
| Creation date | 2003/01/20 |
| Update date | 2024/09/10 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | O-phospho-L-threonine:198-198(MINT-716027) |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Predetermined participant |