Curation Details
Interaction ID: MINT-17354

Unique identifier for interactor Auniprotkb:O96017
Unique identifier for interactor Buniprotkb:P30304
Alternative identifier for interactor Aintact:EBI-1180783
uniprotkb:Q6QA03
uniprotkb:Q6QA04
uniprotkb:Q6QA05
uniprotkb:Q6QA06
uniprotkb:Q6QA07
uniprotkb:Q6QA08
uniprotkb:Q6QA10
uniprotkb:Q6QA11
uniprotkb:Q6QA12
uniprotkb:Q6QA13
uniprotkb:Q9HCQ8
uniprotkb:Q9UGF0
uniprotkb:Q9UGF1
uniprotkb:B7ZBF3
uniprotkb:B7ZBF4
uniprotkb:B7ZBF5
uniprotkb:Q9HBS5
uniprotkb:A8K3Y9
ensembl:ENSP00000385747.1
ensembl:ENSP00000386087.1
ensembl:ENSP00000497000.1
Alternative identifier for interactor Bintact:EBI-747671
uniprotkb:Q8IZH5
uniprotkb:Q96IL3
uniprotkb:Q9H2F2
ensembl:ENSP00000303706.3
Aliases for Apsi-mi:chk2_human(display_long)
uniprotkb:CHEK2(gene name)
psi-mi:CHEK2(display_short)
uniprotkb:CHK2(gene name synonym)
uniprotkb:RAD53(gene name synonym)
uniprotkb:Cds1 homolog(gene name synonym)
uniprotkb:Checkpoint kinase 2(gene name synonym)
uniprotkb:CDS1(gene name synonym)
uniprotkb:CHK2 checkpoint homolog(gene name synonym)
Aliases for Bpsi-mi:mpip1_human(display_long)
uniprotkb:Dual specificity phosphatase Cdc25A(gene name synonym)
uniprotkb:CDC25A(gene name)
psi-mi:CDC25A(display_short)
Interaction detection methodspsi-mi:"MI:0019"(coimmunoprecipitation)
First authorLee et al. (2000)
Identifier of the publicationpubmed:10724175
mint:MINT-5212334
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0217"(phosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7227405
mint:MINT-17354
Confidence scoreintact-miscore:0.62
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:If Cdc25A is phosphorylated on Ser123, it is destructed and DNA synthesis is reduced to 30% as a cell cycle control after gamma irradiation
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
partial coverage:partial coverage
NCBI Taxonomy identifier for the host organismtaxid:-4(in vivo)
taxid:-4(in vivo)
Parameters of the interaction-
Creation date2002/04/19
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant