Curation Details
Interaction ID: MINT-17288

Unique identifier for interactor Auniprotkb:P06730
Unique identifier for interactor Buniprotkb:O60516
Alternative identifier for interactor Aintact:EBI-73440
uniprotkb:D6RCQ6
uniprotkb:B7Z6V1
ensembl:ENSP00000389624.2
intact:EBI-28969298
uniprotkb:Q96E95
Alternative identifier for interactor Bintact:EBI-746950
ensembl:ENSP00000308472.2
Aliases for Apsi-mi:if4e_human(display_long)
uniprotkb:mRNA cap-binding protein(gene name synonym)
uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)
uniprotkb:EIF4E(gene name)
psi-mi:EIF4E(display_short)
uniprotkb:EIF4EL1(gene name synonym)
uniprotkb:EIF4F(gene name synonym)
Aliases for Bpsi-mi:4ebp3_human(display_long)
uniprotkb:EIF4EBP3(gene name)
psi-mi:EIF4EBP3(display_short)
Interaction detection methodspsi-mi:"MI:0019"(coimmunoprecipitation)
First authorPoulin et al. (1998)
Identifier of the publicationmint:MINT-6547867
pubmed:9593750
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8688711
mint:MINT-17288
Confidence scoreintact-miscore:0.90
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:4E-BP3 is a member of the 4E-BP family. These proteins bind eIF4E and prevent its assembly into eIF4F, repressing cap dependent translation.
comment:homomint
comment:mint
NCBI Taxonomy identifier for the host organismtaxid:-4(in vivo)
taxid:-4(in vivo)
Parameters of the interaction-
Creation date2001/09/10
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bbinding-associated region:37-47(MINT-1535233)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant