Curation Details
Interaction ID: MINT-17096

Unique identifier for interactor Auniprotkb:P78314
Unique identifier for interactor Buniprotkb:P27348
Alternative identifier for interactor Aintact:EBI-727062
uniprotkb:O00500
uniprotkb:O15373
uniprotkb:P78315
uniprotkb:A6NNC2
uniprotkb:B2R5R6
uniprotkb:B4DT04
uniprotkb:D3DVR0
intact:EBI-28985856
uniprotkb:D6R919
ensembl:ENSP00000422168.3
Alternative identifier for interactor Bintact:EBI-359854
uniprotkb:Q567U5
uniprotkb:Q5TZU8
uniprotkb:Q9UP48
uniprotkb:D6W4Z5
ensembl:ENSP00000238081.3
ensembl:ENSP00000371267.4
Aliases for Apsi-mi:3bp2_human(display_long)
uniprotkb:SH3BP2(gene name)
psi-mi:SH3BP2(display_short)
uniprotkb:3BP2(gene name synonym)
uniprotkb:RES4-23(orf name)
Aliases for Bpsi-mi:1433t_human(display_long)
uniprotkb:YWHAQ(gene name)
psi-mi:YWHAQ(display_short)
uniprotkb:14-3-3 protein tau(gene name synonym)
uniprotkb:14-3-3 protein T-cell(gene name synonym)
uniprotkb:Protein HS1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorFoucault et al. (2003)
Identifier of the publicationmint:MINT-5216007
pubmed:12501243
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8579674
mint:MINT-17096
Confidence scoreintact-miscore:0.64
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:"\"2H identifies 14-3-3 zheta, epsilon and TAU ( Tau is more expressed in lymphoid tissues)rn- CoIP overexpressing Myc-3BP2 and HA-14-3-3 TAU in COSrn- In vitro pull down with GST-14-3-3 TAUrn- CoIP with endogenous level 3BP2, western with anti 14-3-3 reveals ( in resting mocytic U937 cells)rn- In COS-1 myc-3BP2 and HA-14-3-3 TAU are colocalized with double immunofluorescence and cofocal microscopy ( cytoplasm):rnmapping of interactive serines in two-hybrid: s225A binds poorly, S277A abolishes bindingrn- GST-14-3-3 pull down with 3BP1 mutated in ser225ala ( perturbed binding) or ser277ala ( abolished)rn\""
comment:homomint
comment:domino
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2003/01/20
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor AO-phospho-L-serine:277-277(MINT-725707)
O-phospho-L-serine:225-225(MINT-725705)
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant