Curation Details
Interaction ID: MINT-16696

Unique identifier for interactor Auniprotkb:P41235-2
Unique identifier for interactor Buniprotkb:Q12772
Alternative identifier for interactor Aintact:EBI-9640483
ensembl:ENSP00000412111.1
Alternative identifier for interactor Bintact:EBI-465059
ensembl:ENSP00000354476.4
uniprotkb:Q86V36
uniprotkb:Q6GTH7
uniprotkb:Q9UH04
uniprotkb:Q05BD5
Aliases for Apsi-mi:p41235-2(display_long)
uniprotkb:HNF4A(gene name)
psi-mi:HNF4A(display_short)
uniprotkb:HNF4(gene name synonym)
uniprotkb:NR2A1(gene name synonym)
uniprotkb:Nuclear receptor subfamily 2 group A member 1(gene name synonym)
uniprotkb:TCF14(gene name synonym)
uniprotkb:Transcription factor 14(gene name synonym)
uniprotkb:Transcription factor HNF-4(gene name synonym)
uniprotkb:HNF4-A(isoform synonym)
Aliases for Bpsi-mi:srbp2_human(display_long)
uniprotkb:SREBF2(gene name)
psi-mi:SREBF2(display_short)
uniprotkb:SREBP2(gene name synonym)
uniprotkb:Sterol regulatory element-binding transcription factor 2(gene name synonym)
uniprotkb:BHLHD2(gene name synonym)
uniprotkb:Class D basic helix-loop-helix protein 2(gene name synonym)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorMisawa et al. (2003)
Identifier of the publicationpubmed:12855700
mint:MINT-5216527
imex:IM-27301
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-6965279
mint:MINT-16696
imex:IM-27301-1
Confidence scoreintact-miscore:0.54
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:homomint
comment:mint
figure legend:Fig. 8a
causality statement:P41235 increases activity of Q12772
full coverage:Only protein-protein interactions
dataset:IBD - Inflammatory bowel disease
dataset:Ulcerative colitis - Interactions of proteins identified as having a link to ulcerative colitis
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2003/09/29
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A35s radiolabel:?-?
Feature(s) for interactor Bglutathione s tranferase tag:?-?
sufficient binding region:1-481
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAutoradiography
Participant identification method for interactor BAutoradiography