Curation Details
Interaction ID: MINT-16165

Unique identifier for interactor Auniprotkb:P22681
Unique identifier for interactor Buniprotkb:Q96B97
Alternative identifier for interactor Aintact:EBI-518228
ensembl:ENSP00000264033.3
uniprotkb:A3KMP8
Alternative identifier for interactor Bintact:EBI-346595
uniprotkb:Q8IWX6
uniprotkb:Q8IX98
uniprotkb:Q96RN4
uniprotkb:Q9NYR0
ensembl:ENSP00000380921.3
uniprotkb:B7Z1D5
uniprotkb:Q5JPT4
uniprotkb:Q5JPT5
Aliases for Apsi-mi:cbl_human(display_long)
uniprotkb:Signal transduction protein CBL(gene name synonym)
uniprotkb:Proto-oncogene c-Cbl(gene name synonym)
uniprotkb:Casitas B-lineage lymphoma proto-oncogene(gene name synonym)
uniprotkb:RING finger protein 55(gene name synonym)
uniprotkb:CBL(gene name)
psi-mi:CBL(display_short)
uniprotkb:CBL2(gene name synonym)
uniprotkb:RNF55(gene name synonym)
uniprotkb:RING-type E3 ubiquitin transferase CBL(gene name synonym)
Aliases for Bpsi-mi:sh3k1_human(display_long)
uniprotkb:SH3KBP1(gene name)
psi-mi:SH3KBP1(display_short)
uniprotkb:CIN85(gene name synonym)
uniprotkb:Cbl-interacting protein of 85 kDa(gene name synonym)
uniprotkb:Human Src family kinase-binding protein 1(gene name synonym)
uniprotkb:CD2-binding protein 3(gene name synonym)
Interaction detection methodspsi-mi:"MI:0019"(coimmunoprecipitation)
First authorSoubeyran et al. (2002)
Identifier of the publicationpubmed:11894095
mint:MINT-5215184
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8173159
mint:MINT-16165
Confidence scoreintact-miscore:0.97
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:Upon stimulation with EGF a tricomplex between EGF-CBL-CIN85 is formed.
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
NCBI Taxonomy identifier for the host organismtaxid:-4(in vivo)
taxid:-4(in vivo)
Parameters of the interaction-
Creation date2002/04/16
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor AO4'-phospho-L-tyrosine:731-731(MINT-712541)
binding-associated region:680-906(MINT-712538)
O4'-phospho-L-tyrosine:774-774(MINT-712543)
Feature(s) for interactor Bbinding-associated region:1-330(MINT-712548)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant